Description

CyclopentaneMethanol, 2-[[3-[[(1,1-diMethylethyl)diMethylsilyl]oxy]phenyl]Methyl]-4-[(tetrahydro-2 H-pyran-2-yl)oxy]-3-[3-[(tetrahydro-2H-pyran-2-yl)oxy]-1-octenyl]-, [1S-[1a,2a,3b(1E,3R*),4a]]- is a sophisticated, stereochemically defined synthetic intermediate of significant importance in advanced organic synthesis. Its complex structure, featuring multiple protecting groups, makes it a critical building block for the construction of complex bioactive molecules. This high-purity compound is essential for research and development chemists working in pharmaceutical discovery and fine chemical manufacturing, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), particularly for complex targets.
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, enabling the exploration of complex structure-activity relationships.
• Process Chemistry Development: Serves as a defined intermediate for scaling up synthetic routes under Current Good Manufacturing Practice (cGMP) conditions.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct molecules with specific three-dimensional configurations critical for biological activity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and other high-value compounds requiring precise synthetic control.
• Academic & Institutional Research: Supports cutting-edge synthetic methodology development and chemical biology studies in university and institutional laboratories.

Basic Information

Item	Details
Product Name	CyclopentaneMethanol, 2-[[3-[[(1,1-diMethylethyl)diMethylsilyl]oxy]phenyl]Methyl]-4-[(tetrahydro-2 H-pyran-2-yl)oxy]-3-[3-[(tetrahydro-2H-pyran-2-yl)oxy]-1-octenyl]-, [1S-[1a,2a,3b(1E,3R*),4a]]-
CAS No.	81846-26-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(1S,2S,3R,4S)-2-[[3-[(tert-Butyldimethylsilyl)oxy]phenyl]methyl]-4-[(tetrahydro-2H-pyran-2-yl)oxy]-3-[3-[(tetrahydro-2H-pyran-2-yl)oxy]-1-octen-1-yl]cyclopentanemethanol; [1S-[1a,2a,3b(1E,3R*),4a]]-2-[[3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl]methyl]-4-[(tetrahydro-2H-pyran-2-yl)oxy]-3-[3-[(tetrahydro-2H-pyran-2-yl)oxy]-1-octenyl]cyclopentanemethanol; CAS 81846-26-6; Advanced Chiral Cyclopentane Intermediate; TBS/THP Protected Cyclopentane Synthon.
EINECS	Contact for details

Quality Control

Our high-purity synthetic intermediates are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and chiral purity analysis, to ensure identity, strength, and stereochemical integrity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment. We support development under quality standards appropriate for your project phase, from research use to cGMP.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.