Description

(2R)-5-hydroxy-1,2-dimethyl-4-[(E,4S,6R,8S,9S,10S,11R,12R,13R,14S,15R, 17S,18S,19R,20S,21R,23R,25S,27S,28R,29S,30S,31R)-8,9,11,13,15,17,19,21 ,23,25,27,28,29,30,31-pentadecahydroxy-2,4,6,10,12,14,18,20-octamethyl -32-[(2R,3R,4S,5S,6S)-3,4,5,6-tetrahydroxy-6-[(2R)-2-hydroxyundecyl]ox an-2-yl]dotriacont-2-enoyl]-2H-pyrrol-3-one is a highly complex, stereochemically defined macrolide-pyrrolone hybrid compound. Its intricate polyhydroxylated structure makes it a valuable advanced synthetic intermediate for research into novel bioactive molecules. This high-purity compound is primarily targeted at pharmaceutical R&D and specialty chemical synthesis sectors requiring precise molecular architecture.

Application

• Pharmaceutical Research & Development: As a key chiral building block or precursor for the synthesis of novel drug candidates, particularly in antibiotic and antifungal discovery programs.
• Medicinal Chemistry: For structure-activity relationship (SAR) studies, leveraging its complex polyhydroxylated macrolactone core to explore new pharmacophores.
• Chemical Biology: As a probe or tool compound to study biological pathways and enzyme interactions due to its potential for specific molecular recognition.
• Process Chemistry Development: For scaling up synthetic routes to complex natural product analogs or developing new catalytic methodologies for polyol synthesis.
• Academic Research: In university laboratories for advanced organic synthesis projects and the study of stereoselective reactions.
• High-Value Specialty Chemical Production: As an intermediate in the multi-step synthesis of performance chemicals with specific stereochemical requirements.

Basic Information

Product Name	(2R)-5-hydroxy-1,2-dimethyl-4-[(E,4S,6R,8S,9S,10S,11R,12R,13R,14S,15R, 17S,18S,19R,20S,21R,23R,25S,27S,28R,29S,30S,31R)-8,9,11,13,15,17,19,21 ,23,25,27,28,29,30,31-pentadecahydroxy-2,4,6,10,12,14,18,20-octamethyl -32-[(2R,3R,4S,5S,6S)-3,4,5,6-tetrahydroxy-6-[(2R)-2-hydroxyundecyl]ox an-2-yl]dotriacont-2-enoyl]-2H-pyrrol-3-one
CAS No.	179729-59-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Macrolide-pyrrolone hybrid; Complex polyhydroxylated macrolactone; Stereochemically defined advanced intermediate; CAS 179729-59-0; (2R)-5-hydroxy-1,2-dimethyl-4-[(E,4S,6R,8S,9S,10S,11R,12R,13R,14S,15R, 17S,18S,19R,20S,21R,23R,25S,27S,28R,29S,30S,31R)-8,9,11,13,15,17,19,21 ,23,25,27,28,29,30,31-pentadecahydroxy-2,4,6,10,12,14,18,20-octamethyl -32-[(2R,3R,4S,5S,6S)-3,4,5,6-tetrahydroxy-6-[(2R)-2-hydroxyundecyl]oxan-2-yl]dotriacont-2-enoyl]-2H-pyrrol-3-one
EINECS	Contact for details

Quality Control

This high-purity synthetic intermediate is produced under strict quality control protocols. Each batch is characterized and tested to ensure identity, purity, and stereochemical integrity, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from advanced analytical techniques. Our quality system is designed to support cGMP and ISO guidelines for laboratory and pilot-scale materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider inert atmosphere conditions to preserve stability. Keep container tightly sealed when not in use to prevent moisture absorption or contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.