Description

Neocuproine is a highly selective and sensitive chelating agent and chromogenic reagent, primarily known for its application in the colorimetric determination of copper(I) ions. Its value lies in forming a stable, intensely colored complex with Cu(I), enabling precise analytical detection and quantification in various matrices. This compound is essential for researchers and quality control laboratories in the pharmaceutical, environmental monitoring, and chemical synthesis sectors, where accurate metal ion analysis is critical.

Application

• Analytical Chemistry: As a specific chromogenic reagent for the spectrophotometric detection and assay of cuprous (Cu(I)) ions.
• Biochemical Research: Used in studies of copper-containing enzymes and proteins to selectively chelate and quantify bioavailable copper.
• Pharmaceutical Analysis: Employed in the quality control of drug substances and products to trace residual copper catalysts or impurities.
• Environmental Testing: Applied in water and soil analysis to monitor copper pollution levels and speciation.
• Chemical Synthesis: Serves as a stabilizing ligand for copper in catalytic cycles and organometallic chemistry.
• Material Science: Utilized in the development of sensors and diagnostic kits for copper detection.

Basic Information

Product Name	Neocuproine
CAS No.	484-11-7
Molecular Formula	C₁₄H₁₂N₂
Molecular Weight	208.26 g/mol
Synonyms	2,9-Dimethyl-1,10-phenanthroline; 2,9-Dimethyl-o-phenanthroline; Cuproine; Neocuproin; Dimethylphenanthroline; Cuproin; Bathocuproine (Note: Bathocuproine is a sulfonated derivative, often used interchangeably in context); Nc
EINECS	207-606-9

Quality Control

Our Neocuproine is manufactured under a rigorous quality management system. Each batch is tested to ensure high purity and consistency, meeting the stringent requirements for analytical reagent and research-grade chemicals. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	162 - 166 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Copper Complex Absorbance	Meets performance criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.