Description

(2S,3S,5R)-N-(4-((1S,2S,3S,5R,6R)-3,5-DIAZIDO-2-((2S,3R,5S,6R)-3-AZIDO-6-(AZIDOMETHYL)-4,5-DIHYDROXYTETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLAMINO)BUTYL)-3-HYDROXY-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-2-CARBOXAMIDE is a sophisticated, multi-functional nucleoside analog derivative designed for advanced pharmaceutical research and development. This compound is engineered to serve as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel antiviral and anticancer therapeutics. It is primarily targeted at pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in cutting-edge drug discovery programs.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of next-generation nucleoside-based antiviral drugs.
• Antiviral Drug Discovery: Research and development of novel therapeutics targeting viral polymerases and replication mechanisms.
• Oncology Research: Investigation as a potential prodrug or active component in anticancer regimens, particularly for targeting DNA synthesis in rapidly dividing cells.
• Biochemical Probe: Used in mechanistic studies to understand enzyme inhibition, cell signaling pathways, and nucleotide metabolism.
• Preclinical Development: Serves as a candidate molecule for pharmacokinetic, pharmacodynamic, and toxicology studies.
• Labeled Compound Synthesis: Potential precursor for the preparation of isotopically labeled (e.g., C-13, N-15) analogs for metabolic tracing studies.

Basic Information

Product Name	(2S,3S,5R)-N-(4-((1S,2S,3S,5R,6R)-3,5-DIAZIDO-2-((2S,3R,5S,6R)-3-AZIDO-6-(AZIDOMETHYL)-4,5-DIHYDROXYTETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLAMINO)BUTYL)-3-HYDROXY-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-2-CARBOXAMIDE
CAS No.	948916-28-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	948916-28-7; AZT-Triazole Intermediate; Multi-azido Nucleoside Derivative; Thymidine Azido Analogue; Complex Nucleoside Carboxamide; Antiviral Nucleoside Precursor; Research Compound 948916-28-7
EINECS	Contact for details

Quality Control

This high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity, related substances, and other critical parameters are provided with each shipment. Our quality protocols are designed to support compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) or as specified on the label or COA. This material is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Unknown Impurity	≤ 1.0%
Total Impurities	≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.