Description

5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one, 9,9a-bis(acetyloxy)-3-[(acetyloxy)methyl]-1,1a,1b,2,4a,7a,7b,8,9,9a-decahydro-2,4a,7b-trihydroxy-1,1,6,8-tetramethyl-, [1aR-(1aalpha,1bbeta,2beta,4abeta,7aalpha,7balpha,8alpha,9beta,9aalpha)]- is a complex, high-purity diterpenoid derivative with significant potential in advanced organic synthesis. This compound is valued for its intricate polycyclic framework and multiple functional groups, making it a versatile key intermediate for research and development. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams working on novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Advanced Organic Synthesis: Used as a complex starting material or intermediate for constructing intricate polycyclic natural product analogs and scaffolds.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical entities with potential therapeutic activity.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in laboratories.
• Biochemical Research: Investigated for its potential interactions with biological targets and enzyme systems.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one, 9,9a-bis(acetyloxy)-3-[(acetyloxy)methyl]-1,1a,1b,2,4a,7a,7b,8,9,9a-decahydro-2,4a,7b-trihydroxy-1,1,6,8-tetramethyl-, [1aR-(1aalpha,1bbeta,2beta,4abeta,7aalpha,7balpha,8alpha,9beta,9aalpha)]-
CAS No.	77646-21-0
Molecular Formula	C29H38O10
Molecular Weight	546.61 g/mol
Synonyms	Taxinine; Taxinine I; 5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one, 9,9a-bis(acetyloxy)-3-[(acetyloxy)methyl]-1,1a,1b,2,4a,7a,7b,8,9,9a-decahydro-2,4a,7b-trihydroxy-1,1,6,8-tetramethyl-, (1aR,1bS,2S,4aS,7aS,7bR,8S,9S,9aS)-; (1aR,1bS,2S,4aS,7aS,7bR,8S,9S,9aS)-9,9a-Bis(acetyloxy)-3-[(acetyloxy)methyl]-1,1a,1b,2,4a,7a,7b,8,9,9a-decahydro-2,4a,7b-trihydroxy-1,1,6,8-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one; 2α,5α,7β,9α,10β,13α-Hexaacetoxytaxa-4(20),11-diene
EINECS	Contact for details

Quality Control

Our Taxinine (CAS 77646-21-0) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.