Description

1H-as-Indaceno3,2-doxacyclododecin-7,15-dione, 2-(6-deoxy-2,3,4-tri-O-methyl-.alpha.-L-mannopyranosyl)oxy-13-(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yloxy-9-ethyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetradecahydro-, (2R,3aS,5aR,5bS is a complex, high-purity macrolide derivative with a sophisticated glycosylated structure. This compound is valued for its potential as a key advanced pharmaceutical intermediate or research standard in the development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of fine chemicals for high-value applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel macrolide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in academic and industrial research to study structure-activity relationships (SAR) and biological pathways.
• Medicinal Chemistry: Employed in lead optimization and discovery programs for developing new antibiotics or other therapeutic agents.
• Fine Chemical Synthesis: Acts as a specialized starting material or intermediate for synthesizing complex, high-value organic molecules.
• Process Development: Utilized in scaling up and optimizing synthetic routes for the production of target molecules in pilot and commercial-scale manufacturing.

Basic Information

Item	Details
Product Name	1H-as-Indaceno3,2-doxacyclododecin-7,15-dione, 2-(6-deoxy-2,3,4-tri-O-methyl-.alpha.-L-mannopyranosyl)oxy-13-(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yloxy-9-ethyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetradecahydro-, (2R,3aS,5aR,5bS
CAS No.	131929-65-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Azithromycin Impurity; Azithromycin Related Compound; 9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A; 2'-Deoxy-2'-epi-azithromycin; 2'-Deoxy-2'-epi-N-demethylazithromycin; (2R,3aS,5aR,5bS)-9-Ethyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetradecahydro-2-(6-deoxy-2,3,4-tri-O-methyl-α-L-mannopyranosyl)oxy-13-[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]oxy-1H-as-indaceno[3,2-d]oxacyclododecine-7,15-dione
EINECS	Contact for details

Quality Control

Our 1H-as-Indaceno3,2-doxacyclododecin-7,15-dione derivative is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single unknown impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 5.0% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.