Description

(1R)-6α-Acetyloxy-1,2,3,6,7,7a,10,14,14aβ,14b-decahydro-1α-hydroxy-3,13-dimethoxy-5,5,7aβ,9,14bα-pentamethyl-12H-3β,5aβ-epoxy-5H-furo[3,4-i]oxepino[4,3-a]xanthen-12-one is a high-purity, complex diterpenoid derivative of significant interest in advanced pharmaceutical research and development. Its intricate polycyclic structure makes it a valuable intermediate or reference standard for synthesizing novel bioactive compounds and studying structure-activity relationships. This compound is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of potential drug candidates, particularly in oncology and anti-inflammatory research.
• Reference Standard: Used for analytical method development, validation, and quality control (HPLC, LC-MS) in pharmaceutical manufacturing and regulatory compliance.
• Medicinal Chemistry Research: Employed in lead optimization and pharmacological studies to explore new chemical entities based on the diterpenoid scaffold.
• Biochemical Tool Compound: Utilized in vitro and in vivo studies to investigate specific biological pathways and enzyme interactions.
• Academic Research: Used in university and institutional labs for synthetic organic chemistry projects and natural product derivative studies.
• Process Chemistry Development: Acts as a model compound for scaling up complex synthetic routes under current Good Manufacturing Practice (cGMP) conditions.

Basic Information

Product Name	(1R)-6α-Acetyloxy-1,2,3,6,7,7a,10,14,14aβ,14b-decahydro-1α-hydroxy-3,13-dimethoxy-5,5,7aβ,9,14bα-pentamethyl-12H-3β,5aβ-epoxy-5H-furo[3,4-i]oxepino[4,3-a]xanthen-12-one
CAS No.	81543-05-7
Molecular Formula	C₃₀H₄₀O₉
Molecular Weight	544.64 g/mol
Synonyms	6α-Acetoxy-1α-hydroxy-3,13-dimethoxy-5,5,7aβ,9,14bα-pentamethyl-12-oxo-3β,5aβ-epoxy-5H-furo[3,4-i]oxepino[4,3-a]xanthene; 12-Oxo-5H-furo[3,4-i]oxepino[4,3-a]xanthene derivative; CAS 81543-05-7; (1R,3S,5aS,6S,7aS,14aS,14bR)-6-(Acetyloxy)-1,14a-dihydroxy-3,13-dimethoxy-5,5,7a,9,14b-pentamethyl-12-oxo-1,2,3,5a,6,7,7a,10,14,14a,14b-decahydro-3,5a-epoxyfuro[3,4-i]oxepino[4,3-a]xanthene
EINECS	Contact for details

Quality Control

Our (1R)-6α-Acetyloxy-1,2,3,6,7,7a,10,14,14aβ,14b-decahydro-1α-hydroxy-3,13-dimethoxy-5,5,7aβ,9,14bα-pentamethyl-12H-3β,5aβ-epoxy-5H-furo[3,4-i]oxepino[4,3-a]xanthen-12-one is produced under strict quality management systems. Products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We can supply material compliant with research-grade standards and support development toward cGMP-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.