Description

6H-2,3,5-Trioxapentaleno[1',6':5,6,7]cyclonona[1,2-a]naphthalen-6-one, 10-[(2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl)oxy]-2a,4,4a,6a,7,9,10,11,12,12a,12b,13,14,14b-tetradecahydro-11-hydroxy-2a,12a-dimethyl-, (2aR,4aS,6aR,10R,11R,12aR,12bS,14bR)- is a complex, high-purity organic compound with a defined stereochemistry, primarily recognized as a key intermediate or reference standard in advanced pharmaceutical research. Its intricate fused-ring structure and specific glycosidic linkage make it a valuable building block for the synthesis of novel bioactive molecules, particularly in the development of specialized therapeutics. This compound is essential for research institutions and pharmaceutical companies focused on medicinal chemistry, process development, and analytical method validation.

Application

• Pharmaceutical Intermediate: Serves as a critical synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), especially for complex natural product derivatives.
• Reference Standard: Used as a high-purity analytical standard for quality control, method development, and validation in pharmaceutical laboratories to ensure product identity and purity.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies aimed at discovering new compounds with potential therapeutic activity.
• Process Chemistry: Employed in route scouting and optimization for the scalable synthesis of complex target molecules within R&D and pilot-scale production.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis, glycoscience, and the chemical biology of complex polycyclic systems.

Basic Information

Item	Details
Product Name	6H-2,3,5-Trioxapentaleno[1',6':5,6,7]cyclonona[1,2-a]naphthalen-6-one, 10-[(2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl)oxy]-2a,4,4a,6a,7,9,10,11,12,12a,12b,13,14,14b-tetradecahydro-11-hydroxy-2a,12a-dimethyl-, (2aR,4aS,6aR,10R,11R,12aR,12bS,14bR)-
CAS No.	81474-91-1
Molecular Formula	C30H40O9
Molecular Weight	544.64 g/mol
Synonyms	10-Deacetyl-7-deoxy-10-oxopaclitaxel; 10-Deacetyl-7-deoxy-10-oxotaxol; 7-Deoxy-10-deacetyl-10-oxotaxol; 10-Oxotaxol derivative; 7-Deoxy-10-oxo-10-deacetylbaccatin III derivative; (2aR,4aS,6aR,10R,11R,12aR,12bS,14bR)-10-[(2,6-Dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl)oxy]-2a,4,4a,6a,7,9,10,11,12,12a,12b,13,14,14b-tetradecahydro-11-hydroxy-2a,12a-dimethyl-6H-2,3,5-trioxapentaleno[1',6':5,6,7]cyclonona[1,2-a]naphthalen-6-one
EINECS	Contact for details

Quality Control

Our 6H-2,3,5-Trioxapentaleno[1',6':5,6,7]cyclonona[1,2-a]naphthalen-6-one, 10-[(2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl)oxy]-2a,4,4a,6a,7,9,10,11,12,12a,12b,13,14,14b-tetradecahydro-11-hydroxy-2a,12a-dimethyl-, (2aR,4aS,6aR,10R,11R,12aR,12bS,14bR)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral methods to confirm stereochemical integrity, ensuring it meets the exacting standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Under these conditions, the product is typically stable for at least 24 months. The container should be kept in a dry, well-ventilated area. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.