Description

(E)-2-Methyl-2-butenoic acid [(2aS,12R)-4,5,7aα,9,10,10aβ,11,11aβ-octahydro-12-hydroxy-10-methylene-2,9-dioxo-3H-2a,6-methano-2H-oxete[2',3':4,5]cyclodeca[1,2-b]furan-11α-yl] ester is a high-purity, complex organic ester with significant potential as a key synthetic intermediate. Its intricate polycyclic structure makes it a valuable building block for advanced chemical synthesis, particularly in the development of novel compounds. This product is primarily targeted at research and development organizations and fine chemical manufacturers in the pharmaceutical and agrochemical sectors seeking specialized intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs), especially those with polycyclic or steroidal-like frameworks.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where its unique structure can contribute to novel modes of action.
• Advanced Material Synthesis: Acts as a specialized monomer or building block for creating polymers and materials with specific optical or mechanical properties.
• Academic & Industrial R&D: Employed in chemical research for methodology development, total synthesis projects, and exploring new chemical spaces.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	(E)-2-Methyl-2-butenoic acid [(2aS,12R)-4,5,7aα,9,10,10aβ,11,11aβ-octahydro-12-hydroxy-10-methylene-2,9-dioxo-3H-2a,6-methano-2H-oxete[2',3':4,5]cyclodeca[1,2-b]furan-11α-yl] ester
CAS No.	79404-34-5
Molecular Formula	C₂₀H₂₄O₇
Molecular Weight	376.40 g/mol
Synonyms	2-Butenoic acid, 2-methyl-, (2aS,12R)-4,5,7aα,9,10,10aβ,11,11aβ-octahydro-12-hydroxy-10-methylene-2,9-dioxo-3H-2a,6-methano-2H-oxete[2',3':4,5]cyclodeca[1,2-b]furan-11α-yl ester, (E)-; Tiglic acid ester derivative; (E)-2-Methylcrotonic acid ester; Polycyclic furan ester; Complex lactone ester intermediate.
EINECS	Contact for details

Quality Control

Our (E)-2-Methyl-2-butenoic acid ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture and potential contamination. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.