Description

N-((Z)-1-((2R,3R,4R,5R,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)hexadecanamide is a complex, high-purity glycolipid derivative, specifically a glycosylated ceramide, valued for its role as a key intermediate and reference standard in advanced biochemical research and development. Its precise stereochemistry and functional groups make it a critical compound for studying cell membrane structure, signaling pathways, and sphingolipid metabolism. This material is essential for researchers and developers in the pharmaceutical, biotechnology, and life science sectors focused on lipidomics, drug discovery, and novel therapeutic agent synthesis.

Application

• Biochemical Research & Lipidomics: Serves as a high-purity reference standard and analytical reagent for the identification and quantification of complex sphingolipids in biological samples.
• Pharmaceutical R&D: Used as a critical intermediate in the synthesis of novel therapeutic agents targeting lipid-related pathways, such as those involved in cancer, neurodegenerative diseases, and metabolic disorders.
• Cell Biology Studies: Employed in research to investigate the structure, function, and dynamics of cell membranes, lipid rafts, and glycosphingolipid-mediated cellular signaling.
• Enzyme Substrate/Inhibitor Studies: Acts as a substrate for studying the activity of specific glycosidases, ceramidases, or other enzymes involved in sphingolipid catabolism and anabolism.
• Cosmetic & Dermatological Research: Investigated for potential applications in advanced skincare formulations aimed at modulating skin barrier function and ceramide levels.
• Diagnostic Development: Utilized in the development of diagnostic assays and kits for detecting abnormalities in sphingolipid metabolism.

Basic Information

Item	Details
Product Name	N-((Z)-1-((2R,3R,4R,5R,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)hexadecanamide
CAS No.	77538-38-6
Molecular Formula	C52H97NO14
Molecular Weight	960.33 g/mol
Synonyms	β-Gentiobiosyl-N-(2-hydroxy-3-octadecenyl)-hexadecanamide; Glycosylceramide (specific isomer); Gentiobiosylceramide derivative; Lactosylceramide analog; Glycolipid Ceramide; Sphingolipid intermediate; (2R,3R,4R,5R,6R)-2-[[(2R,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-6-[[(2Z,3S)-2-hexadecanoylamino-3-hydroxyoctadec-4-enoxy]methyl]oxane-3,4-diol
EINECS	Contact for details

Quality Control

Our N-((Z)-1-((2R,3R,4R,5R,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)hexadecanamide is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant standards for high-purity biochemicals, and custom synthesis and purification to specific research-grade specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to reach room temperature before opening to minimize condensation and exposure to atmospheric moisture. For long-term storage under inert atmosphere, please contact us.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.