Description

7H-(1,5,10)Trioxacyclotetradecino(7,8,9-gh)pyrrolizine-2,5,9(8H)-trion e,3,4,11,13,15,16,16a,16b-octahydro-3,4,8-trihydroxy-7-methyl-8-(1-methylethyl)-3-(1-methylpropyl)-, (16aR,16bR)- is a complex, stereochemically defined pyrrolizine alkaloid derivative with a unique polycyclic framework. This compound is of significant interest for its potential as a high-value synthetic intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting complex biological pathways.
• Agrochemical Research: Used in the development of new active ingredients with specific stereochemical requirements for enhanced efficacy.
• Chemical Biology Probe: Serves as a sophisticated scaffold for creating molecular probes to study enzyme mechanisms or receptor interactions.
• Asymmetric Synthesis: Utilized as a chiral starting material or auxiliary in stereoselective synthesis due to its defined (16aR,16bR) configuration.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in total synthesis and natural product analog development.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals requiring a precise, multi-functional core structure.

Basic Information

Item	Details
Product Name	7H-(1,5,10)Trioxacyclotetradecino(7,8,9-gh)pyrrolizine-2,5,9(8H)-trion e,3,4,11,13,15,16,16a,16b-octahydro-3,4,8-trihydroxy-7-methyl-8-(1-methylethyl)-3-(1-methylpropyl)-, (16aR,16bR)-
CAS No.	77156-23-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(16aR,16bR)-3,4,11,13,15,16,16a,16b-Octahydro-3,4,8-trihydroxy-7-methyl-8-(1-methylethyl)-3-(1-methylpropyl)-7H-(1,5,10)trioxacyclotetradecino(7,8,9-gh)pyrrolizine-2,5,9(8H)-trione; CAS 77156-23-1; Pyrrolizine alkaloid derivative; Complex polycyclic lactone.
EINECS	Contact for details

Quality Control

Our 7H-(1,5,10)Trioxacyclotetradecino(7,8,9-gh)pyrrolizine derivative is produced under strict quality management protocols. Every batch undergoes comprehensive analytical characterization to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) are provided, detailing results from tests such as HPLC for purity, NMR and IR for structural confirmation, and chiral analysis. We support cGMP and ISO-aligned standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% de (16aR,16bR)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.