Description

(6R,7S)-7α-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-3-[[[(E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]oxy]methyl]-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a high-purity, semi-synthetic cephalosporin derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for synthesizing novel β-lactam antibiotics, offering a structurally complex scaffold for further chemical modification. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of novel cephalosporin-class antibiotics.
• Antibacterial Research: Used in medicinal chemistry programs to develop new antibacterial compounds with improved efficacy against resistant strains.
• Biochemical Research: Serves as a reference standard or probe in studies investigating β-lactamase inhibition and bacterial cell wall synthesis mechanisms.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value active pharmaceutical ingredients (APIs).
• Analytical Standard: Used as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories.

Basic Information

Product Name	(6R,7S)-7α-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-3-[[[(E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]oxy]methyl]-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS No.	75794-96-6
Molecular Formula	C24H26N4O10S
Molecular Weight	562.55 g/mol
Synonyms	7-Methoxy Cefotaxime Impurity; 7-Methoxy Cefotaxime Intermediate; 7-Methoxy Cefotaxime Derivative; 7-Methoxy Cefotaxime Related Compound; 3-[(E)-3-(4-Hydroxyphenyl)acryloyloxymethyl]-7-methoxy-3-cephem-4-carboxylic Acid Derivative; 7-Methoxy Cefotaxime Side Chain Intermediate; (6R,7S)-7-Methoxy-3-[[[(E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our (6R,7S)-7α-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-3-[[[(E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]oxy]methyl]-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Production can be aligned with cGMP guidelines for pharmaceutical intermediate applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere packing.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.