Description

(6R,7S)-7α-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-7-methoxy-8-oxo-3-[[[(E)-1-oxo-3-[4-(sulfooxy)phenyl]-2-propenyl]oxy]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a complex, semi-synthetic cephalosporin derivative with a sulfated phenolic ester side chain. This compound is of significant interest for its potential as a key intermediate or active pharmaceutical ingredient (API) in advanced antibiotic research and development. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on novel β-lactam antibiotics to address evolving bacterial resistance.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of next-generation cephalosporin antibiotics.
• Antibiotic Research & Development: Used in preclinical and clinical studies to develop new antibacterial agents with enhanced spectra of activity.
• Active Pharmaceutical Ingredient (API): Potential use as the core active component in formulated injectable antibiotic products.
• Biochemical Research: Employed as a tool compound to study bacterial cell wall synthesis and the mechanism of action of β-lactam drugs.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related pharmaceutical products.

Basic Information

Item	Details
Product Name	(6R,7S)-7α-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-7-methoxy-8-oxo-3-[[[(E)-1-oxo-3-[4-(sulfooxy)phenyl]-2-propenyl]oxy]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS No.	75794-94-4
Molecular Formula	C24H28N4O13S2
Molecular Weight	644.62 g/mol
Synonyms	7-Methoxycephalosporin Sulfate Ester; Cephalosporin 87/312; (6R,7S)-3-[[(E)-3-(4-Sulfooxyphenyl)propenoyl]oxymethyl]-7-[(R)-2-(4-amino-4-carboxybutyramido)]-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 7α-Methoxy-7-[2-(2-amino-2-carboxyethylamino)-2-oxoethylamino]cephalosporanic acid 3-(4-sulfooxycinnamoyloxymethyl) derivative; Antibiotic 87/312; SQ 28,516; CP-45,899-1
EINECS	Contact for details

Quality Control

Our (6R,7S)-7α-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-7-methoxy-8-oxo-3-[[[(E)-1-oxo-3-[4-(sulfooxy)phenyl]-2-propenyl]oxy]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, spectroscopic identification (IR, NMR), and tests for specific impurities and residual solvents. Certificates of Analysis (COA) detailing all specifications and results are provided to ensure traceability and compliance with cGMP and relevant pharmacopeial guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.