Description

2-Methylpropenoic acid [(1aR,4E,5aR,8aR,9R,10aS)-10a-acetoxymethyl-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-4-methyl-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl] ester is a highly specialized, complex organic ester derivative of methacrylic acid and a functionalized sesquiterpene lactone core. This compound is of significant interest for its potential as a key synthetic intermediate or a bioactive scaffold in advanced pharmaceutical research and fine chemical synthesis. It is primarily sought by research institutions and development laboratories in the pharmaceutical, agrochemical, and specialty chemical sectors for the creation of novel molecules with targeted biological activities.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its complex, polyfunctional structure.
• Agrochemical Development: Investigated as a precursor for novel active ingredients in crop protection products, leveraging its bioactive sesquiterpene framework.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce specific chiral and functional complexity into target molecules.
• Biochemical Probe Development: Utilized in research to create molecular probes for studying biological pathways and enzyme interactions.

Basic Information

Item	Details
Product Name	2-Methylpropenoic acid [(1aR,4E,5aR,8aR,9R,10aS)-10a-acetoxymethyl-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-4-methyl-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl] ester
CAS No.	75680-34-1
Molecular Formula	C21H26O7
Molecular Weight	390.43 g/mol
Synonyms	Methacrylic acid, (1aR,4E,5aR,8aR,9R,10aS)-10a-(acetoxymethyl)-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-4-methyl-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl ester; Parthenolide methacrylate ester; Parthenolide 9-methacrylate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our high-purity specialty chemicals are produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to confirm identity and purity, ensuring it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This compound is light-sensitive and may be prone to hydrolysis; store under an inert atmosphere if specified. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.