Description

(3R,4aS,9aS)-3-[[(1R)-1-(3-Furyl)-6,7-dihydro-3β-hydroxy-1H,3H-3aα,7aα-methanoisobenzofuran-4-yl]methyl]-3,4,4a,9a-tetrahydro-3-hydroxy-5,5,9a-trimethyl-1,2-dioxino[4,3-c]oxepin-7(5H)-one is a complex, high-purity organic compound with a defined stereochemistry, serving as a critical advanced pharmaceutical intermediate or reference standard. Its intricate molecular architecture makes it essential for the research and development of novel therapeutic agents, particularly in specialized synthetic pathways. This compound is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of proprietary drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control (QC) in pharmaceutical manufacturing to ensure batch consistency.
• Medicinal Chemistry Research: Serves as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the efficient production of target active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Utilized in universities and research institutes for studies in organic synthesis, asymmetric catalysis, and natural product analog development.

Basic Information

Product Name	(3R,4aS,9aS)-3-[[(1R)-1-(3-Furyl)-6,7-dihydro-3β-hydroxy-1H,3H-3aα,7aα-methanoisobenzofuran-4-yl]methyl]-3,4,4a,9a-tetrahydro-3-hydroxy-5,5,9a-trimethyl-1,2-dioxino[4,3-c]oxepin-7(5H)-one
CAS No.	73703-76-1
Molecular Formula	C30H34O8
Molecular Weight	522.59 g/mol
Synonyms	1,2-Dioxino[4,3-c]oxepin-7(5H)-one derivative; CAS 73703-76-1; Methanoisobenzofuran-oxepinone derivative; (3R,4aS,9aS)-Isomer of the specified oxepinone; Complex furan-isobenzofuran-oxepin tricyclic intermediate
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes. We support cGMP-compliant manufacturing for advanced applications, ensuring traceability and documentation meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.