Description

1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride is a high-purity pharmaceutical intermediate and a key derivative of the cephalosporin class of antibiotics. This compound is critical for the synthesis and research of advanced β-lactam antibiotics, offering a sophisticated chemical scaffold for further modification. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing novel antibacterial agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of advanced-generation cephalosporin antibiotics.
• Active Pharmaceutical Ingredient (API) Research: Serves as a precursor in the development and study of new antibacterial compounds with potentially enhanced efficacy.
• Biochemical Research: Used in studies investigating the structure-activity relationships (SAR) of β-lactam antibiotics and mechanisms of bacterial resistance.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized chemical entities in the life sciences sector.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical production.

Basic Information

Item	Details
Product Name	1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride
CAS No.	73547-70-3
Molecular Formula	C22H25ClN6O7S2 • HCl
Molecular Weight	625.96 g/mol (for monohydrochloride salt)
Synonyms	7β-[2-(2-Aminothiazol-4-yl)-2-(Z)-(1-carboxy-1-methylethoxyimino)acetamido]-3-(pyridinium-1-ylmethyl)ceph-3-em-4-carboxylate chloride hydrochloride; Cefepime Impurity; Cefepime Related Compound; (6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(1-carboxy-1-methylethoxyimino)acetamido]-3-(pyridinium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate chloride hydrochloride; Cefepime Pyridinium Intermediate; 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium dichloride
EINECS	Contact for details

Quality Control

Our 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.