Description

16β-(Acetyloxy)-3β-[[4-O-[4-O-(3-O,4-O-diacetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl)-2,6-dideoxy-β-D-ribo-hexopyranosyl]-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy]-14-hydroxy-5β-card-20(22)-enolide is a highly specialized cardiac glycoside derivative, representing a key intermediate in advanced pharmaceutical research and synthesis. This compound is critical for the development and study of novel therapeutic agents targeting cardiovascular conditions. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel cardiac glycosides and related therapeutic agents.
• Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase (Na+/K+-ATPase) inhibition and cardiac pharmacology.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new compounds with optimized efficacy and safety profiles.
• Academic Research: Utilized in university and institutional labs for fundamental research on heart failure treatments and ion channel modulators.
• Process Development: Acts as a key intermediate for scaling up the production of complex, high-value active pharmaceutical ingredients (APIs).
• Reference Material: Supplied as a high-purity compound for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	16β-(Acetyloxy)-3β-[[4-O-[4-O-(3-O,4-O-diacetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl)-2,6-dideoxy-β-D-ribo-hexopyranosyl]-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy]-14-hydroxy-5β-card-20(22)-enolide
CAS No.	7242-09-3
Molecular Formula	C47H68O19
Molecular Weight	913.04 g/mol
Synonyms	Acetyldigitoxin-α; 3'''-O-Acetyldigitoxin; 16β-Acetoxy-3β-[(O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide; α-Acetyldigitoxin; Digitoxin 16-acetate; 16-Acetyldigitoxin; 16-O-Acetyldigitoxin; 3'''-Monoacetyldigitoxin
EINECS	Contact for details

Quality Control

Our production of 16β-(Acetyloxy)-3β-[[4-O-[4-O-(3-O,4-O-diacetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl)-2,6-dideoxy-β-D-ribo-hexopyranosyl]-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy]-14-hydroxy-5β-card-20(22)-enolide adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Maximum Impurity	≤ 2.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.