Description

17Beta-Hydroxy-4-Androsten-3-One 17-D-Glucuronide is a key conjugated metabolite of testosterone, formed via glucuronidation in the liver. This compound is of significant value as a high-purity reference standard and analytical reagent for clinical and forensic toxicology. It is primarily required by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and contract research organizations (CROs) specializing in endocrinology and anti-doping analysis.

Application

• Reference Standard for Analytical Testing: Primary use as a certified reference material (CRM) for the quantification of testosterone metabolites in biological matrices via LC-MS/MS or GC-MS.
• Clinical Diagnostics: Calibration and quality control in diagnostic assays measuring androgen profiles for endocrine disorder assessment.
• Forensic & Anti-Doping Analysis: Essential for the accurate identification and confirmation of testosterone abuse in sports drug testing programs.
• Pharmaceutical Metabolism & Pharmacokinetics (DMPK) Studies: Used to study the metabolic pathways, conjugation, and excretion profiles of synthetic androgens.
• Biochemical Research: Investigation of steroid hormone conjugation enzymes (UGT) and their activity in vitro.

Basic Information

Product Name	17Beta-Hydroxy-4-Androsten-3-One 17-D-Glucuronide
CAS No.	1180-25-2
Molecular Formula	C25H36O8
Molecular Weight	464.55 g/mol
Synonyms	Testosterone 17β-D-Glucuronide; Testosterone Glucuronide; 17β-Hydroxyandrost-4-en-3-one 17β-D-glucuronide; Androst-4-en-17β-ol-3-one 17β-D-glucuronide; Testosterone 17-Glucuronide; NSC 113986; Testosterone 17β-Glucuronoside
EINECS	214-646-7

Quality Control

Our 17Beta-Hydroxy-4-Androsten-3-One 17-D-Glucuronide is manufactured under strict quality management systems. Each batch is subjected to rigorous identity, purity, and impurity profile testing using advanced chromatographic (HPLC, UPLC) and spectroscopic (NMR, MS) techniques to ensure it meets the stringent requirements for use as an analytical reference standard. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.