Description

Dl-Normetanephrine Hydrochloride CAS NO 1011-74-1 is a hydrochloride salt of a key catecholamine metabolite, serving as a crucial reference standard and biochemical reagent. This compound is essential for analytical research and quality control in the pharmaceutical and life sciences sectors, where precise measurement of catecholamine pathways is required. It is primarily utilized by researchers, diagnostic manufacturers, and QC laboratories involved in neurochemistry, clinical diagnostics, and drug development.

Application

• Pharmaceutical Reference Standard: Used for the calibration and validation of analytical methods (e.g., HPLC, LC-MS) in drug development and quality control.
• Clinical Diagnostics: Serves as a critical calibrator and control in assays for measuring catecholamine metabolites (like normetanephrine) in urine or plasma, aiding in the diagnosis of pheochromocytoma and other neuroendocrine tumors.
• Biochemical Research: Employed in studies of adrenergic signaling, neurotransmitter metabolism, and enzymatic activity related to catechol-O-methyltransferase (COMT).
• In-vitro Diagnostics (IVD) Manufacturing: A key raw material in the production of test kits and reagents for clinical laboratory use.
• Metabolomics & Biomarker Discovery: Used as a known standard in metabolic profiling to identify and quantify related compounds in biological samples.

Basic Information

Product Name	Dl-Normetanephrine Hydrochloride
CAS No.	1011-74-1
Molecular Formula	C9H14ClNO3
Molecular Weight	219.66 g/mol
Synonyms	DL-Normetanephrine HCl; (±)-Normetanephrine Hydrochloride; 3-Methoxy-4-hydroxyphenylethanolamine Hydrochloride; 4-Hydroxy-3-methoxyphenylethanolamine Hydrochloride; 3-O-Methyladrenaline Hydrochloride; DL-3-Methoxy-4-hydroxyphenylethanolamine Hydrochloride; DL-4-Hydroxy-3-methoxyphenylethanolamine Hydrochloride; DL-3-O-Methyladrenaline Hydrochloride
EINECS	213-795-4

Quality Control

Our Dl-Normetanephrine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and diagnostic applications. A Certificate of Analysis (COA) detailing specific results for purity, identity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.