Description

Dextrorphan D-Tartrate is the tartrate salt form of dextrorphan, a key pharmaceutical intermediate and reference standard. This compound is of significant importance in the research and development of central nervous system (CNS) active agents and analytical chemistry. It is primarily utilized by pharmaceutical manufacturers, research institutions, and analytical laboratories for synthesis, method development, and quality control processes.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced pharmaceutical compounds, particularly those targeting neurological pathways.
• Analytical Reference Standard: Used for the identification, assay, and impurity profiling in quality control (QC) and research and development (R&D) laboratories via techniques like HPLC and GC.
• Metabolite Studies: Serves as a reference metabolite in pharmacokinetic and pharmacodynamic research related to dextromethorphan and similar compounds.
• Neuroscience Research: Employed in biochemical and pharmacological studies to investigate NMDA receptor antagonism and related neurological mechanisms.
• Method Development & Validation: Essential for developing and validating analytical methods in compliance with regulatory guidelines (e.g., ICH, FDA).

Basic Information

Product Name	Dextrorphan D-Tartrate
CAS No.	125-73-5
Molecular Formula	C₁₇H₂₃NO • C₄H₆O₆
Molecular Weight	443.46 g/mol
Synonyms	Dextrorphan Tartrate; (+)-3-Hydroxy-N-methylmorphinan Tartrate; (9α,13α,14α)-3-Hydroxy-17-methylmorphinan Tartrate; Dextrorphan Acid Tartrate; Dextrorphan Hydrogen Tartrate; NSC 82116; d-3-Hydroxy-N-methylmorphinan Tartrate
EINECS	204-754-5

Quality Control

Our Dextrorphan D-Tartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting high-purity standards suitable for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, chiral purity, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Chiral Purity (HPLC)	≥99.0%
Water (KF)	≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.