Description

Pseudomorphine (Morphine Impurity) is a significant chemical reference standard and impurity of the opioid analgesic morphine. This compound is critical for pharmaceutical research, development, and quality control, where precise identification and quantification of impurities are paramount. It is primarily used by analytical laboratories, pharmaceutical manufacturers, and regulatory bodies to ensure the safety, purity, and efficacy of morphine-based drug substances and products.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the calibration of analytical instruments and validation of testing methods in pharmacopeial compliance (e.g., USP, EP).
• Impurity Profiling & Control: Essential for the identification, qualification, and quantification of Pseudomorphine as a specified impurity in morphine active pharmaceutical ingredients (APIs) and finished dosage forms.
• Method Development & Validation: Serves as a key analyte in developing and validating stability-indicating HPLC, UPLC, or GC methods for morphine and related opiates.
• Stability Studies: Employed in forced degradation studies to understand the degradation pathways of morphine and to establish appropriate storage conditions and shelf life.
• Forensic & Clinical Toxicology: Used as an analytical standard in forensic laboratories for the precise analysis of opiates in biological samples and seized materials.
• Academic & Process Research: Utilized in chemical and pharmacological research to study the metabolism, synthesis, and degradation mechanisms of morphine alkaloids.

Basic Information

Item	Details
Product Name	Pseudomorphine (Morphine Impurity)
CAS No.	125-24-6
Molecular Formula	C34H36N2O6
Molecular Weight	568.66 g/mol
Synonyms	Pseudomorphine; Dehydromorphine; Morphine Dimer; Oxydimorphine; 2,2'-Bimorphine; 4,4'-Dihydroxy-3,3'-dimethoxy-17,17'-dimethyl-9a,9'a-(iminoethanoimino)difuro[3,4-e]isoquinoline; Morphine Impurity F (EP); Morphine Related Compound C (USP)
EINECS	204-742-5

Quality Control

Every batch of Pseudomorphine (Morphine Impurity) is manufactured and analyzed under strict quality management systems. We provide comprehensive support for pharmaceutical applications, with quality standards aligned to current industry and regulatory expectations. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual unknown impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.