Description

(6R)-7α-[[[[(1,3-Dimethylureido)carbonyl]amino]phenylacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a key advanced pharmaceutical intermediate, specifically a cephalosporin derivative, essential for the synthesis of modern β-lactam antibiotics. Its complex structure provides the foundational scaffold for developing potent antibacterial agents with enhanced stability and efficacy. This high-purity compound is primarily required by pharmaceutical R&D laboratories and manufacturers engaged in the production of next-generation cephalosporin drugs.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of advanced cephalosporin antibiotics.
• Antibacterial Drug Development: Used in research and development of new β-lactam antibiotics targeting resistant bacterial strains.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the multi-step synthesis of final drug substances.
• Process Chemistry & Scale-up: Employed in optimizing and scaling manufacturing processes for cephalosporin-based pharmaceuticals.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory submissions.
• Academic & Contract Research: Supports biochemical and pharmacological studies in academic and CRO settings.

Basic Information

Product Name	(6R)-7α-[[[[(1,3-Dimethylureido)carbonyl]amino]phenylacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS No.	68779-06-6
Molecular Formula	C₂₃H₂₆N₁₀O₆S₂
Molecular Weight	626.65 g/mol
Synonyms	7β-[(Phenylacetyl)amino]-3-[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid derivative; Cephalosporin derivative 68779-06-6; (6R,7R)-7-[[(Phenylacetyl)amino]]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid urea analog; 7-ADCA urea tetrazole derivative; 7-ACA intermediate analog; Tetrazolylthiomethyl cephalosporin; Ureido carbonyl phenylacetyl cephalosporin intermediate.
EINECS	Contact for details

Quality Control

Our (6R)-7α-[[[[(1,3-Dimethylureido)carbonyl]amino]phenylacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediates. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.