Description

Cyclopentanone, 2-[[3-[[(1,1-diMethylethyl)dimethylsilyl]oxy]phenyl]methyl]-4-[(tetrahydro-2H-pyran-2-yl)oxy]-3-[3-[(tetrahydro-2H-pyran-2-yl)oxy]-1-octenyl]-, [2R-[2a,3b(1E,3S*),4a]]- is a sophisticated, high-value synthetic intermediate characterized by its complex stereochemistry and multiple protecting groups. This compound matters for its critical role in the multi-step synthesis of complex organic molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing intricate molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for complex, stereochemically-defined targets.
• Agrochemical Synthesis: Used in research for developing advanced pesticides or herbicides with specific chiral activity.
• Chemical Biology & Probe Development: Serves as a precursor for creating molecular probes to study biological pathways and enzyme functions.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the commercial production of fine chemicals.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological development in organic synthesis and catalysis.
• Custom Synthesis & Contract Manufacturing: A critical component for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	Cyclopentanone, 2-[[3-[[(1,1-diMethylethyl)dimethylsilyl]oxy]phenyl]methyl]-4-[(tetrahydro-2H-pyran-2-yl)oxy]-3-[3-[(tetrahydro-2H-pyran-2-yl)oxy]-1-octenyl]-, [2R-[2a,3b(1E,3S*),4a]]-
CAS No.	65423-57-6
Molecular Formula	C33H52O5Si
Molecular Weight	556.85 g/mol
Synonyms	(2R,3S,4R)-2-[[3-[(tert-Butyldimethylsilyl)oxy]phenyl]methyl]-4-[(tetrahydro-2H-pyran-2-yl)oxy]-3-[3-[(tetrahydro-2H-pyran-2-yl)oxy]-1-octen-1-yl]cyclopentanone; CAS 65423-57-6; 2-[[3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl]methyl]-4-[(tetrahydro-2H-pyran-2-yl)oxy]-3-[3-[(tetrahydro-2H-pyran-2-yl)oxy]-1-octenyl]cyclopentanone, [2R-[2α,3β(1E,3S*),4α]]-; (1E,2R,3S,4R)-2-((3-((tert-Butyldimethylsilyl)oxy)benzyl)-4-((tetrahydro-2H-pyran-2-yl)oxy)-3-(3-((tetrahydro-2H-pyran-2-yl)oxy)oct-1-en-1-yl)cyclopentan-1-one; THP-protected cyclopentanone silyl ether derivative.
EINECS	Contact for details

Quality Control

Our Cyclopentanone derivative (CAS 65423-57-6) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR (1H and 13C), and mass spectrometry, to confirm identity, stereochemical purity, and impurity profile. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is between 2°C and 8°C (refrigerated). Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.