Description

[(1S,3Z,4aS,11R,11aR,12S,12aR)-3-(amino-hydroxy-methylidene)-4a,6,7,12-tetrahydroxy-11-methyl-2,4,5-trioxo-11,11a,12,12a-tetrahydro-1H-tetracen-1-yl]-dimethyl-azanium chloride is a high-purity, complex tetracycline derivative salt of significant interest in advanced pharmaceutical research and development. Its intricate stereochemistry and functional groups make it a valuable chemical intermediate for synthesizing novel therapeutic agents. This compound is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers focused on antibiotic development and molecular discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel tetracycline-class antibiotics and other bioactive molecules.
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Utilized in studies investigating bacterial protein synthesis inhibition and mechanisms of antibiotic action.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of more complex, functionally modified tetracycline derivatives.

Basic Information

Product Name	[(1S,3Z,4aS,11R,11aR,12S,12aR)-3-(amino-hydroxy-methylidene)-4a,6,7,12-tetrahydroxy-11-methyl-2,4,5-trioxo-11,11a,12,12a-tetrahydro-1H-tetracen-1-yl]-dimethyl-azanium chloride
CAS No.	61281-03-6
Molecular Formula	C25H27ClN2O9
Molecular Weight	534.95 g/mol
Synonyms	7-Dimethylamino-6-demethyl-6-deoxytetracycline hydrochloride; DMCT hydrochloride; 6-Deoxy-6-demethyltetracycline hydrochloride, dimethylamino-; Demethylchlorotetracycline impurity standard; (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hydrochloride; 6-Deoxy-6-demethyltetracycline HCl; 6-Demethyl-6-deoxytetracycline hydrochloride; 7-(Dimethylamino)-6-demethyl-6-deoxytetracycline monohydrochloride
EINECS	Contact for details

Quality Control

Our [(1S,3Z,4aS,11R,11aR,12S,12aR)-3-(amino-hydroxy-methylidene)-4a,6,7,12-tetrahydroxy-11-methyl-2,4,5-trioxo-11,11a,12,12a-tetrahydro-1H-tetracen-1-yl]-dimethyl-azanium chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and related substances, to ensure it meets stringent specifications for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.