Description

(6R)-3-[[[(S)-2-Amino-2-carboxy-1,1-dimethylethyl]thio]methyl]-7α-[[(R)-5-amino-5-carboxy-1-oxopentyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a complex, semi-synthetic β-lactam compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical intermediate or precursor in the synthesis of novel cephalosporin antibiotics, offering a pathway to compounds with potentially enhanced efficacy and resistance profiles. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on next-generation anti-infective therapies. The compound's intricate structure allows for targeted modifications to address specific bacterial challenges.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of advanced-generation cephalosporin antibiotics.
• Antibiotic Research & Development: Used as a reference standard or starting material in R&D programs aimed at discovering new antibacterial agents with improved spectra of activity.
• Structure-Activity Relationship (SAR) Studies: Employed to investigate the correlation between the molecular structure of β-lactams and their antimicrobial potency.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing high-value, specialized active pharmaceutical ingredients (APIs).
• Biochemical Research: May be used in studies exploring bacterial cell wall synthesis and the mechanisms of β-lactamase inhibition.

Basic Information

Item	Details
Product Name	(6R)-3-[[[(S)-2-Amino-2-carboxy-1,1-dimethylethyl]thio]methyl]-7α-[[(R)-5-amino-5-carboxy-1-oxopentyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS No.	60857-71-8
Molecular Formula	C20H28N4O8S2
Molecular Weight	516.59 g/mol
Synonyms	7β-[(R)-2-Amino-2-carboxyethylthioacetamido]-3-[(S)-1-carboxy-1-methylethylthiomethyl]-3-cephem-4-carboxylic acid; Cephalosporin C derivative; (6R,7R)-7-[[(2R)-2-Amino-3-carboxy-1-oxopropyl]amino]-3-[[(1S)-2-amino-1,1-dimethyl-2-oxoethyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Antibiotic intermediate 60857-71-8
EINECS	Contact for details

Quality Control

Every batch of this high-purity pharmaceutical intermediate is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications for assay, related substances, residual solvents, and other critical parameters. Our quality standards are designed to meet the rigorous demands of pharmaceutical R&D and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.