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(3R,5S,7R,8S,9S,10S,12S,13R,14S,17R)-17-[(2R)-6,7-dihydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol CAS NO 6127-75-9


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CAS No.:6127-75-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(3R,5S,7R,8S,9S,10S,12S,13R,14S,17R)-17-[(2R)-6,7-dihydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol is a high-purity, multi-hydroxylated sterol derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for synthesizing and studying complex bioactive molecules, particularly in the fields of endocrinology and metabolic regulation. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precisely characterized building blocks for drug discovery and process development.

Application

  • Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel steroid-based therapeutics.
  • Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related steroid compounds.
  • Biochemical Research: Employed in studies investigating steroid hormone biosynthesis, metabolism, and receptor interactions.
  • Process Chemistry: Serves as a starting material or intermediate in the multi-step synthesis of complex natural products and active pharmaceutical ingredients (APIs).
  • Academic Research: Utilized in universities and research institutes for exploring new synthetic pathways and biological activities of polyhydroxylated sterols.

Basic Information

Product Name (3R,5S,7R,8S,9S,10S,12S,13R,14S,17R)-17-[(2R)-6,7-dihydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol
CAS No. 6127-75-9
Molecular Formula C27H46O5
Molecular Weight 450.66 g/mol
Synonyms 3β,7α,12α-Trihydroxy-5β-cholestan-26-oic Acid (lactone form derivative); 3,7,12-Trihydroxycholestanoic acid derivative; 5β-Cholestane-3α,7α,12α-triol-26-oate; Nor-dihydrocapsaicin sterol analog; Tetrahydroxylated cholestane; Sterol triol intermediate; Cholestanetriol
EINECS Contact for details

Quality Control

Our (3R,5S,7R,8S,9S,10S,12S,13R,14S,17R)-17-[(2R)-6,7-dihydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to confirm identity and purity, ensuring it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 97.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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