Description

[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate is a high-purity, biologically active nucleotide derivative essential for advanced life science research and pharmaceutical development. This compound serves as a critical building block and research tool for studying cellular energy transfer, signal transduction, and nucleic acid metabolism. It is primarily utilized by biopharmaceutical companies, academic research institutions, and diagnostic manufacturers for applications in enzymology, molecular biology, and the development of novel therapeutics.

Application

• Biochemical Research: As a substrate or cofactor in enzymatic assays to study kinase, polymerase, and other ATP-dependent enzyme activities.
• Pharmaceutical Development: A key intermediate in the synthesis of nucleotide-based prodrugs and antiviral or anticancer agents targeting cellular metabolism.
• Diagnostic Reagent Manufacturing: Used in the formulation of high-sensitivity assay kits for measuring cellular energy status (e.g., ATP/ADP/AMP levels) and metabolic profiling.
• Cell Signaling Studies: Investigation of purinergic signaling pathways and the role of extracellular nucleotides in physiological and pathological processes.
• Metabolomics & Systems Biology: A certified reference standard for the accurate quantification of nucleotide pools in complex biological samples via LC-MS or HPLC.
• Enzyme Engineering & Screening: Essential for high-throughput screening platforms to discover and characterize novel enzymes or inhibitors in drug discovery pipelines.

Basic Information

Product Name	[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate
CAS No.	56983-24-5
Molecular Formula	C20H29N10O22P5
Molecular Weight	928.37 g/mol
Synonyms	P1,P5-Di(adenosine-5') pentaphosphate; Diadenosine pentaphosphate; Ap5A; Adenosine-5'-pentaphospho-5'-adenosine; Diadenosine-5',5'''-P1,P5-pentaphosphate; 5',5'''-P1,P5-Di(adenosine) pentaphosphate; P1,P5-Bis(5'-adenosyl) pentaphosphate; APPPPA
EINECS	Contact for details

Quality Control

Our [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at low temperature. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.