Description

Luzindole CAS NO 117946-91-5 is a potent and selective antagonist of the melatonin MT2 receptor, serving as a critical pharmacological tool for neuroendocrine and circadian rhythm research. Its high specificity makes it invaluable for elucidating the distinct roles of melatonin receptor subtypes in various physiological and pathological processes. This compound is essential for researchers and developers in the fields of neuroscience, endocrinology, and pharmaceutical development.

Application

• Neuroscience Research: Used to study the role of melatonin signaling in sleep regulation, mood disorders, and neurodegenerative diseases.
• Endocrinology Studies: Employed as a selective MT2 receptor blocker to investigate hormonal regulation and circadian biology.
• Pharmacological Tool Compound: Serves as a standard reference antagonist in receptor binding assays and functional studies to validate new drug candidates.
• Academic & Institutional Research: A key reagent for universities and research institutes exploring chronobiology and neuropharmacology.
• Pharmaceutical R&D: Utilized in the discovery and development of novel therapeutics targeting melatonin pathways for insomnia, depression, or cancer.
• In Vitro & In Vivo Models: Applied in cell-based assays and animal studies to dissect specific MT2 receptor-mediated effects.

Basic Information

Product Name	Luzindole
CAS No.	117946-91-5
Molecular Formula	C19H20N2O2
Molecular Weight	308.38 g/mol
Synonyms	N-Acetyl-2-benzyltryptamine; 2-Benzyl-N-acetyltryptamine; N-[2-(1H-Indol-3-yl)ethyl]-N-(phenylmethyl)acetamide; Luzindolum; BMS-214,778; MT2 Receptor Antagonist; Melatonin Receptor Antagonist
EINECS	Contact for details

Quality Control

Our Luzindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.