Description

n-Tris(Hydroxymethyl)Methyl-2-Aminoethanesulfonic Acid is a high-purity biochemical reagent widely recognized as TES. This compound is a zwitterionic buffer with excellent buffering capacity in the physiological pH range, offering minimal interference with biological systems. It is essential for researchers and manufacturers in biopharmaceuticals, molecular biology, and diagnostic kit production who require precise pH control and stability in sensitive biochemical processes.

Application

• Biochemical & Molecular Biology Research: A key component in cell culture media, electrophoresis buffers, and enzyme reaction mixtures.
• Pharmaceutical Formulation: Used as a buffering agent in the development and manufacturing of injectable drugs and vaccines.
• Diagnostic Reagents: Provides stable pH conditions in buffers for clinical diagnostic assays and kits.
• Protein Purification & Analysis: Employed in chromatography elution buffers and protein crystallization studies.
• Tissue Culture: Maintains physiological pH in media for cultivating mammalian and plant cells.
• Cosmetic Formulations: Acts as a pH stabilizer and conditioning agent in high-end skincare products.

Basic Information

Item	Detail
Product Name	n-Tris(Hydroxymethyl)Methyl-2-Aminoethanesulfonic Acid
CAS No.	7365-44-8
Molecular Formula	C6H15NO6S
Molecular Weight	229.25 g/mol
Synonyms	TES; N-[Tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid; 2-[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]ethanesulfonic acid; Tris(hydroxymethyl)methylaminoethanesulfonic acid; (2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-methanesulfonic acid; Biological Buffer TES; Good's Buffer TES
EINECS	230-906-5

Quality Control

Our TES buffer is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, titration for assay, and loss on drying, to ensure it meets stringent specifications for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed lot-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (Titration)	≥ 99.0 %
pH (1% Solution)	4.5 - 5.5
Loss on Drying	≤ 0.5 %
Residue on Ignition	≤ 0.1 %
Heavy Metals (as Pb)	≤ 10 ppm
UV Absorbance (260 nm)	≤ 0.05
UV Absorbance (280 nm)	≤ 0.05

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.