Description

(4S,6'S,11R)-6'-Ethyl-2,3,4,5,5',6,6',7,8,8aα,9α,10-dodecahydro-6'-methoxy-2-methylspiro[1H-4,10aα-methanopentaleno[1,6-cd]azonine-11,3'(4'H)-[2H]-pyran]-9-carboxylic acid methyl ester is a complex, high-purity spirocyclic organic compound of significant interest in advanced pharmaceutical research and development. Its intricate molecular architecture makes it a valuable key intermediate or reference standard for synthesizing novel therapeutic agents. This compound is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the discovery of new bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potential drug candidates, particularly in medicinal chemistry programs.
• Reference Standard: Used for analytical method development, validation, and quality control (QC/QA) in research and production settings.
• Biochemical Research: Employed in studies investigating structure-activity relationships (SAR) and biological pathways due to its unique spiro-fused ring system.
• Process Chemistry Development: Acts as a key material for scaling up synthetic routes from laboratory to pilot plant scale.
• Academic Research: Utilized in universities and institutes for advanced organic synthesis projects and the exploration of new chemical methodologies.

Basic Information

Product Name	(4S,6'S,11R)-6'-Ethyl-2,3,4,5,5',6,6',7,8,8aα,9α,10-dodecahydro-6'-methoxy-2-methylspiro[1H-4,10aα-methanopentaleno[1,6-cd]azonine-11,3'(4'H)-[2H]-pyran]-9-carboxylic acid methyl ester
CAS No.	54370-35-3
Molecular Formula	C24H35NO4
Molecular Weight	401.54 g/mol
Synonyms	Methyl (4S,6'S,11R)-6'-ethyl-6'-methoxy-2-methyl-2,3,4,5,5',6,6',7,8,8aα,9α,10-dodecahydrospiro[1H-4,10aα-methanopentaleno[1,6-cd]azonine-11,3'(4'H)-[2H]pyran]-9-carboxylate; Spiro[1H-4,10aα-methanopentaleno[1,6-cd]azonine-11,3'(4'H)-[2H]pyran]-9-carboxylic acid, 6'-ethyl-2,3,4,5,5',6,6',7,8,8aα,9α,10-dodecahydro-6'-methoxy-2-methyl-, methyl ester, (4S,6'S,11R)-; CAS 54370-35-3
EINECS	Contact for details

Quality Control

Our (4S,6'S,11R)-6'-Ethyl-2,3,4,5,5',6,6',7,8,8aα,9α,10-dodecahydro-6'-methoxy-2-methylspiro[1H-4,10aα-methanopentaleno[1,6-cd]azonine-11,3'(4'H)-[2H]-pyran]-9-carboxylic acid methyl ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Single Unknown Impurity	≤ 1.0%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.