Description

(S)-3,4,4a,5,18,19-hexahydro-9,21,22,26-tetramethoxy-4-methyl-2H-1,24:12,15-dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloicosino[2,3,4-ij]isoquinoline is a complex, high-purity alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical advanced intermediate or reference standard for the synthesis and study of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and pharmacology.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex active pharmaceutical ingredients (APIs) targeting neurological or oncological pathways.
• Reference Standard: Used for analytical method development, validation, and quality control (HPLC, LC-MS) in pharmaceutical manufacturing.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of new drug candidates.
• Biochemical Research: Investigated for its interaction with specific biological targets (e.g., receptors, enzymes) in vitro to elucidate mechanisms of action.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale under GMP-like conditions.

Basic Information

Product Name	(S)-3,4,4a,5,18,19-hexahydro-9,21,22,26-tetramethoxy-4-methyl-2H-1,24:12,15-dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloicosino[2,3,4-ij]isoquinoline
CAS No.	40039-47-2
Molecular Formula	C34H38N2O6
Molecular Weight	570.68 g/mol
Synonyms	Vincamine Impurity; Vincamine Related Compound; (S)-Vincamine Derivative; 3α,16α-Eburnamenine-14,15-diol, 14,15-Epoxy-14β,15β-dihydro- (8CI); Tetrahydrovincamine; Eburnamonine-14,15-diol 14,15-epoxide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (S)-3,4,4a,5,18,19-hexahydro-9,21,22,26-tetramethoxy-4-methyl-2H-1,24:12,15-dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloicosino[2,3,4-ij]isoquinoline is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.