Description

Pilocarpidine is a naturally occurring imidazole alkaloid derived from the leaves of *Pilocarpus* species. This compound serves as a key intermediate in the synthesis of pilocarpine, a critical pharmaceutical agent used primarily in ophthalmology. It is essential for manufacturers in the pharmaceutical and fine chemical sectors requiring high-purity, reliable building blocks for active pharmaceutical ingredient (API) production. Our supply ensures consistent quality and traceability for your critical synthesis processes.

Application

• Pharmaceutical Intermediate: Primary use as a precursor in the commercial synthesis of pilocarpine hydrochloride and nitrate APIs.
• Ophthalmic Drug Manufacturing: Integral to producing medications for treating glaucoma and inducing miosis during ocular surgery.
• Research & Development: Used in biochemical research to study muscarinic acetylcholine receptor agonists and their pathways.
• Fine Chemical Synthesis: Serves as a chiral building block for developing other specialized imidazole-based compounds.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for pharmacopeial testing.

Basic Information

Product Name	Pilocarpidine
CAS No.	127-67-3
Molecular Formula	C10H14N2O2
Molecular Weight	194.23 g/mol
Synonyms	Pilocarpidine; (3S,4R)-3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one; Pilocarpidine; Isopilocarpine; d-Pilocarpine; 2(3H)-Furanone, 3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydro-, (3S,4R)-; NSC 82100
EINECS	204-860-7

Quality Control

Our Pilocarpidine is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for pharmaceutical intermediates. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Specifications can be aligned with customer requirements, including those for GMP or USP-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.