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(6R,7S)-7α-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-3-[[[3-(4-hydroxyphenyl)-2-methoxy-1-oxo-2-propenyl]oxy]methyl]-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid CAS NO 34279-77-1
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CAS No.:34279-77-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(6R,7S)-7α-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-3-[[[3-(4-hydroxyphenyl)-2-methoxy-1-oxo-2-propenyl]oxy]methyl]-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a high-purity, semi-synthetic cephalosporin derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for synthesizing novel β-lactam antibiotics, offering a structurally complex scaffold for further chemical modification. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation antibacterial agents.
Application
- Pharmaceutical Intermediate: Key building block for the synthesis of advanced-generation cephalosporin antibiotics.
- Antibacterial Research: Used in R&D for studying structure-activity relationships (SAR) and developing new β-lactamase inhibitors.
- Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
- Chemical Synthesis: Utilized in organic synthesis for exploring novel chemical modifications to the cephalosporin core.
- Biochemical Studies: Employed in microbiological and biochemical research to investigate mechanisms of bacterial resistance.
Basic Information
| Item | Details |
|---|---|
| Product Name | (6R,7S)-7α-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-3-[[[3-(4-hydroxyphenyl)-2-methoxy-1-oxo-2-propenyl]oxy]methyl]-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| CAS No. | 34279-77-1 |
| Molecular Formula | C27H30N4O11S |
| Molecular Weight | 618.61 g/mol |
| Synonyms | 7α-Methoxy-7-(5-aminoglutaramido)-3-[(E)-3-(4-hydroxyphenyl)-2-methoxypropenoyloxymethyl]-3-cephem-4-carboxylic acid; Cefmenoxime Impurity; Cefmenoxime Related Compound; (6R,7S)-7-Methoxy-7-[(R)-2-amino-2-carboxyethylamino]-3-[[(E)-3-(4-hydroxyphenyl)-2-methoxypropenoyl]oxymethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; SC 34362 (related); Antibiotic SC 34362 derivative |
| EINECS | Contact for details |
Quality Control
Our (6R,7S)-7α-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-3-[[[3-(4-hydroxyphenyl)-2-methoxy-1-oxo-2-propenyl]oxy]methyl]-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 95.0% |
| Related Substances (HPLC) | Total impurities ≤ 5.0% Any single unknown impurity ≤ 1.0% |
| Water Content (KF) | ≤ 5.0% |
| Residue on Ignition | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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