Description

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-2-[2-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-4-thiazolyl]-2-(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)- is a high-purity, advanced pharmaceutical intermediate with a complex cephalosporin-like core structure. Its primary value lies in its role as a critical building block for the synthesis of next-generation β-lactam antibiotics, particularly those designed to combat resistant bacterial strains. This compound is essential for research institutions and pharmaceutical manufacturers focused on developing novel antimicrobial agents and fine chemical synthesis.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: A key intermediate in the production of advanced cephalosporin-class antibiotics.
• Antimicrobial Research & Development: Serves as a core scaffold for designing and testing new compounds against multidrug-resistant bacteria.
• Process Chemistry & Scale-Up: Used in optimizing synthetic routes for the commercial manufacturing of complex β-lactam drugs.
• Fine Chemical Production: Employed in the synthesis of specialized, high-value chemical entities for pharmaceutical applications.
• Reference Standard: Can be utilized as a chromatographic or spectroscopic standard for quality control and analytical method development.

Basic Information

Product Name	5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-2-[2-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-4-thiazolyl]-2-(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-
CAS No.	2489535-06-8
Molecular Formula	C24H24N8O9S3
Molecular Weight	664.69 g/mol
Synonyms	(6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2Z)-2-[2-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-4-thiazolyl]-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Advanced Cephalosporin Intermediate; Cephalosporin C-7 Side Chain Derivative; (Z)-O-Methyl Oxime Cephalosporin Synthon; Amino Thiazolyl Methoxyimino Acetamido Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up processes. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles. We support compliance with cGMP guidelines where applicable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.