Description

2H-Imidazol-2-one, 1-[(4S)-2-(4-fluoro-3,5-dimethylphenyl)-4,5,6,7-tetrahydro-4-methyl-2H-pyrazolo[4,3-c]pyridin-3-yl]-3-(4-fluoro-1-methyl-1H-indazol-5-yl)-1,3-dihydro- is a high-purity, complex heterocyclic compound designed for advanced pharmaceutical research and development. This molecule is of significant interest as a key synthetic intermediate or potential active pharmaceutical ingredient (API) in the discovery of novel therapeutics. It is primarily targeted at R&D scientists and process chemists working in the pharmaceutical and biotechnology sectors, particularly those focused on oncology, CNS disorders, or other disease areas requiring sophisticated small-molecule modulators.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of target drug candidates.
• Active Pharmaceutical Ingredient (API) Research: Used in preclinical and early-stage clinical research as a potential therapeutic agent.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship (SAR) explorations to optimize potency, selectivity, and pharmacokinetic properties.
• Process Chemistry & Scale-Up: Provides a defined chemical entity for developing and optimizing robust, scalable synthetic routes.
• Reference Standard: Acts as a high-purity analytical standard for method development, quality control, and regulatory submissions.
• Biochemical Research: Utilized in vitro and in vivo studies to investigate biological pathways and mechanisms of action.

Basic Information

Product Name	2H-Imidazol-2-one, 1-[(4S)-2-(4-fluoro-3,5-dimethylphenyl)-4,5,6,7-tetrahydro-4-methyl-2H-pyrazolo[4,3-c]pyridin-3-yl]-3-(4-fluoro-1-methyl-1H-indazol-5-yl)-1,3-dihydro-
CAS No.	2212022-56-3
Molecular Formula	C27H26F2N8O
Molecular Weight	516.55 g/mol
Synonyms	1-[(4S)-2-(4-Fluoro-3,5-dimethylphenyl)-4,5,6,7-tetrahydro-4-methyl-2H-pyrazolo[4,3-c]pyridin-3-yl]-3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2H-imidazol-2-one; CAS 2212022-56-3; (4S)-3-[3-(4-Fluoro-1-methyl-1H-indazol-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl]-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine; 1,3-Dihydro-2H-imidazol-2-one derivative (based on structure).
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material that meets the stringent requirements for pharmaceutical research, with typical purity levels exceeding 95% (by HPLC). Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Production and quality systems are designed to support development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the certificate of analysis. This compound is likely light-sensitive and may be hygroscopic; store in a cool, dry place under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.