Description

(R)-N-(2,6-Di([1,1':3',1''-terphenyl]-5'-yl)-4-oxido-7a,8,9,10,11,11a,12,13,14,15-decahydrodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)-1,1,1-trifluoromethanesulfonamide is a sophisticated chiral organophosphorus compound designed for advanced catalytic and synthetic applications. Its value lies in its unique structural framework, which incorporates a sterically demanding, electron-rich dinaphthodioxaphosphepin core, making it an exceptional ligand or catalyst precursor for asymmetric transformations. This high-value specialty chemical is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereocontrol in complex molecule synthesis.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, cross-coupling, and C-H activation.
• As a key intermediate or catalyst precursor in the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• For research and development of novel asymmetric catalytic systems in academic and industrial laboratories.
• In the development of specialty polymers and advanced materials where chiral induction is critical for performance.
• As a building block for creating more complex, functionalized organocatalysts or ligands.
• For process optimization and scale-up studies in fine chemical and custom manufacturing.

Basic Information

Product Name	(R)-N-(2,6-Di([1,1':3',1''-terphenyl]-5'-yl)-4-oxido-7a,8,9,10,11,11a,12,13,14,15-decahydrodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)-1,1,1-trifluoromethanesulfonamide
CAS No.	2152685-54-4
Molecular Formula	C61H45F3NO5PS
Molecular Weight	991.04 g/mol
Synonyms	(R)-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-amine Derivative; (R)-BINOL-Derived Triflyl Phosphoramidate Ligand; (R)-H8-BINOL-Based Dioxaphosphepin; (R)-N-Trifluoromethanesulfonyl Phosphoramidic Acid Ester; (R)-Terphenyl-Substituted Phosphoramidate; (R)-DTB-BINOL Phosphoramidate Analog; Ligand 2152685-54-4; (R)-Chiral Dioxaphosphepin Catalyst
EINECS	Contact for details

Quality Control

Every batch of this high-purity specialty chemical is produced and analyzed under strict quality management protocols. Standard quality control includes comprehensive characterization by NMR (1H, 13C, 31P), HPLC, and mass spectrometry to confirm identity, chiral purity (enantiomeric excess), and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications. We support development and cGMP manufacturing needs with custom synthesis and rigorous analytical validation services.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product in a freezer at -20°C to -10°C under an inert atmosphere (argon or nitrogen). The compound is moisture-sensitive (hygroscopic) and should be handled in a dry environment. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.