Description

1,3,5,2,4-Trioxadisilocino7,6-bpyrrole-7(6H)-carboxylic acid, 8-(1Z)-1-cyano-2-hydroxyethenyltetrahydro-2,2,4,4-tetrakis(1-methylethyl)-, 1,1-dimethylethyl ester, (6aR,8R,9aS)- is a high-purity, stereochemically defined organosilicon heterocyclic compound with a complex, multi-functional molecular architecture. Its unique structure, featuring a fused trioxadisilinocane and pyrrole ring system with cyano and ester functionalities, makes it a valuable advanced intermediate for sophisticated chemical synthesis. This compound is primarily targeted at research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients or functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex heterocycles.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its unique silicon-containing core for enhanced properties.
• Advanced Material Synthesis: Acts as a precursor for specialty polymers, coatings, or hybrid organic-inorganic materials (ORMOSILs) due to its hydrolyzable siloxane linkages and organic functional groups.
• Ligand & Catalyst Development: The defined stereochemistry and multiple heteroatoms make it a candidate for developing novel chiral ligands or organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems, where the cyano and ester groups allow for further derivatization.

Basic Information

Product Name	1,3,5,2,4-Trioxadisilocino7,6-bpyrrole-7(6H)-carboxylic acid, 8-(1Z)-1-cyano-2-hydroxyethenyltetrahydro-2,2,4,4-tetrakis(1-methylethyl)-, 1,1-dimethylethyl ester, (6aR,8R,9aS)-
CAS No.	284490-18-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	tert-Butyl (6aR,8R,9aS)-8-[(1Z)-1-cyano-2-hydroxyvinyl]tetrahydro-2,2,4,4-tetraisopropyl-1,3,5,2,4-trioxadisilocino[7,6-b]pyrrole-7(6H)-carboxylate; (6aR,8R,9aS)-1,1-Dimethylethyl 8-[(1Z)-1-cyano-2-hydroxyethenyl]tetrahydro-2,2,4,4-tetrakis(1-methylethyl)-1,3,5,2,4-trioxadisilocino[7,6-b]pyrrole-7(6H)-carboxylate; CAS 284490-18-2; Trioxadisilocinopyrrole Carboxylate Ester Derivative; Silicon-Containing Pyrrole Ester Intermediate; Chiral Siloxane-Pyrrole Hybrid Compound.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and potential decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.