Description

PyridiniuM, 4-[2-[[(6R,7R)-2-carboxy-7-[[(2Z)-2-(ethoxyiMino)-2-[5-(phosphonoaMino)-1,2,4-thiadiazol-3-yl]acetyl]aMino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-Methyl-, inner salt is a complex, advanced pharmaceutical intermediate belonging to the cephalosporin class of β-lactam antibiotics. This compound is of critical importance for its role in the synthesis of next-generation, broad-spectrum antibacterial agents designed to combat resistant pathogens. It is primarily required by pharmaceutical R&D laboratories and active pharmaceutical ingredient (API) manufacturers engaged in the development of novel anti-infective therapies.

Application

• Key Intermediate in Cephalosporin Synthesis: Serves as a crucial building block for the production of advanced-generation cephalosporin antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and synthesis of new antibacterial compounds with enhanced efficacy.
• Active Pharmaceutical Ingredient (API) Manufacturing: Incorporated into the final chemical synthesis steps for target antibiotic APIs.
• Combinatorial Chemistry Libraries: Utilized in creating focused libraries for high-throughput screening against bacterial targets.
• Process Chemistry & Scale-Up Studies: Essential for optimizing synthetic routes from laboratory to pilot and commercial production scales.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	PyridiniuM, 4-[2-[[(6R,7R)-2-carboxy-7-[[(2Z)-2-(ethoxyiMino)-2-[5-(phosphonoaMino)-1,2,4-thiadiazol-3-yl]acetyl]aMino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-Methyl-, inner salt
CAS No.	229016-73-3
Molecular Formula	C22H26N9O10PS3+ • (Inner Salt)
Molecular Weight	Contact for details
Synonyms	(6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-(ethoxyimino)acetamido]-3-[(1-methyl-4-pyridinio)thio]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 5'-(Dihydrogen Phosphate); Cephalosporin Intermediate 229016-73-3; 4-[2-[[(6R,7R)-2-Carboxy-8-oxo-7-[2-(2-aminothiazol-4-yl)-2-(ethoxyimino)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]pyridin-1-ium-1-yl]methyl Dihydrogen Phosphate (Inner Salt); Phosphonoaminothiadiazolyl Cephalosporin Intermediate; Advanced Cephalosporin Synthon
EINECS	Contact for details

Quality Control

Our pharmaceutical-grade intermediates are produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and impurity profiling, to ensure it meets the stringent requirements for use in API synthesis. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with every shipment. Production can be aligned with cGMP guidelines for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.