Description

1H-Pyrrole-1,2-dicarboxylic acid, 3-amino-4-(6aR,8R,9aS)-7-(1,1-dimethylethoxy)carbonylhexahydro-2,2,4,4-tetrakis(1-methylethyl)-1,3,5,2,4-trioxadisilocino7,6-bpyrrol-8-yl-, 2-ethyl 1-(phenylmethyl) ester is a sophisticated, high-purity organic intermediate featuring a complex pyrrole core integrated with a protected siloxane moiety. This compound is of significant value for its role in the synthesis of novel pharmaceutical candidates and advanced functional materials. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex heterocyclic compounds.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides requiring specific stereochemistry and functional groups.
• Material Science Research: Serves as a precursor for developing novel organic-inorganic hybrid materials and polymers with siloxane linkages.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and probes for studying biological mechanisms and drug-target interactions.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of high-value specialty chemicals.
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and catalysis involving pyrrole derivatives.

Basic Information

Item	Information
Product Name	1H-Pyrrole-1,2-dicarboxylic acid, 3-amino-4-(6aR,8R,9aS)-7-(1,1-dimethylethoxy)carbonylhexahydro-2,2,4,4-tetrakis(1-methylethyl)-1,3,5,2,4-trioxadisilocino7,6-bpyrrol-8-yl-, 2-ethyl 1-(phenylmethyl) ester
CAS No.	222854-86-6
Molecular Formula	C38H61N3O9Si2
Molecular Weight	760.1 g/mol
Synonyms	3-Amino-4-[(6aR,8R,9aS)-7-[(tert-butoxy)carbonyl]hexahydro-2,2,4,4-tetraisopropyl-1,3,5,2,4-trioxadisilocino[7,6-b]pyrrol-8-yl]-1H-pyrrole-1,2-dicarboxylic acid 2-ethyl 1-benzyl ester; 1H-Pyrrole-1,2-dicarboxylic acid, 3-amino-4-[(6aR,8R,9aS)-7-[(1,1-dimethylethoxy)carbonyl]hexahydro-2,2,4,4-tetrakis(1-methylethyl)-1,3,5,2,4-trioxadisilocino[7,6-b]pyrrol-8-yl]-, 2-ethyl 1-(phenylmethyl) ester; tert-Butyl (6aR,8R,9aS)-8-(3-amino-1-(benzyloxycarbonyl)-1H-pyrrole-2,5-dicarboxylate-4-yl)hexahydro-2,2,4,4-tetraisopropyl-1,3,5,2,4-trioxadisilocino[7,6-b]pyrrole-7-carboxylate; CAS 222854-86-6.
EINECS	Contact for details

Quality Control

This high-value intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity suitable for sensitive synthetic applications. Our rigorous testing includes advanced chromatographic and spectroscopic methods to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (where applicable), and residual solvent levels is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.