Description

5H-1,3-Dioxolo4,5-cpyrrole-5-carboxylic acid, 4-4-amino-5-cyano-1-(phenylmethoxy)carbonyl-1H-pyrrol-3-yl-6-(1,1-dimethylethyl)dimethylsilyloxymethyltetrahydro-2,2-dimethyl-, 1,1-dimethylethyl ester, (3aS,4S,6R,6aR)- is a highly functionalized, stereochemically defined pyrrole derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its complex molecular architecture, featuring multiple protected functional groups and a chiral backbone, makes it an invaluable building block for constructing sophisticated target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel drug candidates, particularly for complex small-molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Reagent: Serves as a versatile chiral synthon in academic and industrial laboratories for constructing complex molecular frameworks.
• Material Science Precursor: Potential use in the development of specialty polymers and functional organic materials due to its reactive sites.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of fine chemicals.

Basic Information

Product Name	5H-1,3-Dioxolo4,5-cpyrrole-5-carboxylic acid, 4-4-amino-5-cyano-1-(phenylmethoxy)carbonyl-1H-pyrrol-3-yl-6-(1,1-dimethylethyl)dimethylsilyloxymethyltetrahydro-2,2-dimethyl-, 1,1-dimethylethyl ester, (3aS,4S,6R,6aR)-
CAS No.	222631-46-1
Molecular Formula	C32H42N4O7Si
Molecular Weight	622.80 g/mol
Synonyms	(3aS,4S,6R,6aR)-4-[4-Amino-5-cyano-1-[(phenylmethoxy)carbonyl]-1H-pyrrol-3-yl]-6-[[(1,1-dimethylethyl)dimethylsilyl]oxymethyl]tetrahydro-2,2-dimethyl-5H-1,3-dioxolo[4,5-c]pyrrole-5-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl (3aS,4S,6R,6aR)-4-(4-amino-5-cyano-1-((((benzyloxy)carbonyl)amino)carbonyl)-1H-pyrrol-3-yl)-6-((tert-butyldimethylsilyloxy)methyl)tetrahydro-2,2-dimethyl-5H-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylate; CAS 222631-46-1; Advanced Pyrrole Ester Intermediate; Cbz-Protected Pyrrole Building Block.
EINECS	Contact for details

Quality Control

Our 5H-1,3-Dioxolo4,5-cpyrrole-5-carboxylic acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and NMR for structural confirmation, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.