Description

(6R,7R)-7-[[2-(3-chlorophenyl)acetyl]amino]-3-[(4,4-dimethyl-2,3,5,6-tetrahydropyrazine-1-carbothioyl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate is a sophisticated cephalosporin-based advanced pharmaceutical intermediate. This compound is critical for the synthesis of next-generation β-lactam antibiotics, offering a key structural framework for developing potent antibacterial agents. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on antibiotic development and novel drug synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced cephalosporin antibiotics.
• Antibacterial Drug Research: Serves as a core scaffold for developing new compounds targeting resistant bacterial strains.
• Process Chemistry & Scale-Up: Used in route development and optimization for commercial antibiotic manufacturing.
• Academic & Institutional Research: Employed in medicinal chemistry programs studying structure-activity relationships (SAR) of β-lactams.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	(6R,7R)-7-[[2-(3-chlorophenyl)acetyl]amino]-3-[(4,4-dimethyl-2,3,5,6-tetrahydropyrazine-1-carbothioyl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
CAS No.	22561-27-9
Molecular Formula	C24H26ClN5O5S3
Molecular Weight	604.14 g/mol
Synonyms	7-[(3-Chlorophenylacetamido)]-3-[(4,4-dimethyl-2,3,5,6-tetrahydropyrazine-1-carbothioylthio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cephalosporin derivative intermediate; 3-[(4,4-Dimethyl-1,2,3,6-tetrahydropyrazine-1-carbothioylthio)methyl]-7-[(3-chlorophenylacetamido)]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 22561-27-9; (6R,7R)-7-[(3-Chlorophenylacetamido)]-3-[(4,4-dimethyl-2,3,5,6-tetrahydropyrazine-1-carbothioylthio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. We adhere to strict in-process controls and final release specifications. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.