Description

5-(6-aminopurin-9-yl)-2-[[[[3-[2-(2-butanoylsulfanylethylcarbamoyl)ethylcarbamoyl]-3-hydroxy-2,2-dimethyl-propoxy]-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-4-hydroxy-oxolan-3-yl]oxyphosphonic acid is a sophisticated nucleotide analog with a complex, multi-functional structure designed for advanced biochemical research and pharmaceutical development. This compound matters for its potential role as a key intermediate or active moiety in the synthesis of novel therapeutics, particularly in areas like antiviral or anticancer drug discovery. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing next-generation nucleotide-based treatments and high-purity biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral or anticancer nucleotide analog drugs.
• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies to investigate metabolic pathways and nucleotide processing.
• Pro-drug Development: Acts as a key component in the design of pro-drugs, where its complex structure can be engineered for targeted delivery and controlled activation.
• Life Science Reagents: Formulated into high-purity reagents for molecular biology and cell-based assays requiring specific nucleotide modifications.
• Antisense Oligonucleotide Synthesis: Potential use as a modified monomer in the solid-phase synthesis of advanced antisense or siRNA oligonucleotides for genetic research.

Basic Information

Item	Details
Product Name	5-(6-aminopurin-9-yl)-2-[[[[3-[2-(2-butanoylsulfanylethylcarbamoyl)ethylcarbamoyl]-3-hydroxy-2,2-dimethyl-propoxy]-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-4-hydroxy-oxolan-3-yl]oxyphosphonic acid
CAS No.	2140-48-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Adenosine triphosphate analog; Modified ATP derivative; Nucleotide prodrug intermediate; 9H-Purin-6-amine, N-[2-[[[2-[[3-[(2-[[2-[(1-oxobutyl)thio]ethyl]amino]-2-oxoethyl)amino]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl]oxy(hydroxy)phosphoryl]oxy]methyl]-4-(phosphonooxy)-2-tetrahydrofuranyl]-; Complex nucleotide phosphonate; Custom nucleotide synthesis building block
EINECS	Contact for details

Quality Control

Our 5-(6-aminopurin-9-yl)-2-[[[[3-[2-(2-butanoylsulfanylethylcarbamoyl)ethylcarbamoyl]-3-hydroxy-2,2-dimethyl-propoxy]-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-4-hydroxy-oxolan-3-yl]oxyphosphonic acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets exacting research and development standards. Certificates of Analysis (COA) with detailed chromatographic data and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.