Description

3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-4-Methyl-5-[2-(Phosphonooxy)Ethyl]Thiazolium is a phosphorylated derivative of thiamine, a key biochemical intermediate. This compound is of significant interest in pharmaceutical research and development, particularly in the study of vitamin B1 metabolism and its therapeutic applications. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in advanced synthesis and metabolic pathway analysis.

Application

• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of novel thiamine analogs and prodrugs for pharmaceutical applications.
• Biochemical Research: Used as a reference standard and reagent in studies investigating thiamine metabolism, enzymatic phosphorylation, and cellular energy pathways.
• Nutraceutical Development: Employed in R&D for advanced nutritional supplements targeting specific metabolic functions.
• Diagnostic Reagents: Potential use in the formulation of diagnostic kits and assays for measuring thiamine-related enzymatic activity.
• Veterinary Medicine: Applied in research for developing specialized vitamin formulations for animal health.
• Enzyme Cofactor Studies: Essential for in vitro studies of thiamine-dependent enzymes like transketolase and pyruvate dehydrogenase.

Basic Information

Item	Details
Product Name	3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-4-Methyl-5-[2-(Phosphonooxy)Ethyl]Thiazolium
CAS No.	10023-48-0
Molecular Formula	C13H19N4O4PS
Molecular Weight	358.35 g/mol
Synonyms	Thiamine Monophosphate; Thiamine Phosphate; Vitamin B1 Monophosphate; Thiamine Diphosphate precursor; TMP; Aneurin Monophosphate; 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium Phosphate
EINECS	233-034-0

Quality Control

Our 3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-4-Methyl-5-[2-(Phosphonooxy)Ethyl]Thiazolium is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.