Description

Chondroitin AC Lyase is a highly specific enzyme that catalyzes the eliminative cleavage of chondroitin sulfates A and C, producing unsaturated disaccharides. This precise biochemical action makes it an indispensable tool for structural analysis and quality control of glycosaminoglycan (GAG) preparations. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries who require accurate characterization of chondroitin sulfate sources and their derivatives.

Application

• Glycosaminoglycan (GAG) Analysis: Used for the specific depolymerization and structural elucidation of chondroitin sulfate chains in research and quality control laboratories.
• Pharmaceutical R&D: Employed in the study of chondroitin sulfate's role in joint health, inflammation, and neural development, aiding in drug discovery.
• Nutraceutical Quality Assurance: Critical for verifying the purity, molecular weight, and sulfation pattern of chondroitin sulfate raw materials used in dietary supplements.
• Biomaterial Characterization: Used to analyze chondroitin sulfate components in tissue engineering scaffolds and hydrogel formulations.
• Diagnostic Reagent Manufacturing: Serves as a key component in enzymatic assay kits designed to measure chondroitin sulfate levels in biological samples.
• Enzymatic Production of Oligosaccharides: Facilitates the controlled production of defined, unsaturated chondroitin sulfate oligosaccharides for biochemical studies.

Basic Information

Item	Detail
Product Name	Chondroitin AC Lyase
CAS No.	9047-57-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Chondroitinase AC; Chondroitin AC Lyase; Chondroitinase AC I; Chondroitin Sulfate Lyase AC; Chondroitin ABC Lyase (from *Flavobacterium heparinum*); EC 4.2.2.5; Chondroitin Sulfate Degrading Enzyme
EINECS	Contact for details

Quality Control

Our Chondroitin AC Lyase is produced and tested under stringent conditions to ensure high enzymatic activity, specificity, and lot-to-lot consistency suitable for research and industrial applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing activity units, purity, and stability data. We adhere to relevant quality management standards to guarantee product integrity and performance reliability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Activity)	Conforms (Specific activity provided on COA)
Protein Content (Biuret)	≥ 90%
Specific Activity	≥ 50 units/mg protein
Solubility	Soluble in water or appropriate buffer
Endotoxin Level	< 1.0 EU/μg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.