Description

Tetrahydropterin is a crucial biochemical cofactor and a key intermediate in the biosynthesis of essential biological molecules. This compound matters for its fundamental role in enzymatic processes, particularly as a precursor in the synthesis of tetrahydrobiopterin, a vital coenzyme for aromatic amino acid hydroxylases and nitric oxide synthases. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for biochemical research, enzyme studies, and the development of therapeutic agents.

Application

• Biochemical Research: Used as a critical reagent and standard in studies of pterin metabolism and related enzymatic pathways.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of tetrahydrobiopterin and related therapeutic compounds.
• Enzyme Cofactor Studies: Essential for in vitro assays and research on phenylalanine, tyrosine, and tryptophan hydroxylases.
• Diagnostic Reagent Manufacturing: Employed in the production of kits for diagnosing metabolic disorders related to pterin biosynthesis.
• Nitric Oxide Synthase Research: Utilized in cardiovascular and neurological research to study the NO synthesis pathway.
• Reference Standard: Acts as a high-purity analytical standard for quality control in pharmaceutical and research laboratories.

Basic Information

Product Name	Tetrahydropterin
CAS No.	1008-35-1
Molecular Formula	C9H13N5O3
Molecular Weight	239.23 g/mol
Synonyms	Dihydrobiopterin; 5,6,7,8-Tetrahydropterin; 2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridine; THP; 6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydropterin; 5,6,7,8-Tetrahydro-6-(1,2-dihydroxypropyl)pterin
EINECS	213-758-4

Quality Control

Our Tetrahydropterin is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere such as argon or nitrogen, as the compound is easily oxidized and light-sensitive. Keep the container in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.