Description

(R)-(1-(4-fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-1,4,5,6,7,8-hexahydro-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone is a sophisticated, high-purity small molecule building block designed for advanced research and development. This compound is critical for medicinal chemistry programs, particularly in the discovery of novel therapeutic agents targeting complex disease pathways. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions engaged in drug discovery and chemical biology.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor or scaffold in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery projects.
• Chemical Biology Probe: Acts as a tool compound for investigating specific biological targets and signaling pathways in vitro.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the synthesis of complex molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.
• Academic Research: Utilized in university laboratories for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	(R)-(1-(4-fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-1,4,5,6,7,8-hexahydro-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone
CAS No.	1496510-51-0
Molecular Formula	C28H23F4N5O3S
Molecular Weight	593.57 g/mol
Synonyms	(4aR)-1-(4-Fluorophenyl)-6-[(1-methyl-1H-pyrazol-4-yl)sulfonyl]-4a-{[4-(trifluoromethyl)pyridin-2-yl]carbonyl}-1,4,4a,5,6,7,8,8a-octahydropyrazolo[3,4-g]isoquinoline; (R)-Methanone, (1-(4-fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-1,4,5,6,7,8-hexahydro-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)-2-pyridinyl)-; CAS 1496510-51-0; 1496510-51-0; Pyrazolo[3,4-g]isoquinoline derivative; Advanced pharmaceutical intermediate 1496510-51-0.
EINECS	Contact for details

Quality Control

Our (R)-(1-(4-fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-1,4,5,6,7,8-hexahydro-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.