N-[(11bR)-2,6-Bis([1,1'-biphenyl]-4-yl)-8,9,10,11,12,13,14,15-octahydro-4-oxidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]-1,1,1-trifluoromethanesulfonamide CAS NO 1261302-63-9

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CAS No.:1261302-63-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N-[(11bR)-2,6-Bis([1,1'-biphenyl]-4-yl)-8,9,10,11,12,13,14,15-octahydro-4-oxidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]-1,1,1-trifluoromethanesulfonamide is a sophisticated chiral organophosphorus compound designed for advanced chemical synthesis. This high-value intermediate is critical for research and development in pharmaceutical chemistry, particularly in the creation of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures with high stereochemical fidelity.

Application

Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, especially for central nervous system (CNS) and oncology targets.
Ligand Precursor: Serves as a precursor for the development of specialized chiral ligands used in asymmetric catalysis.
Agrochemical Research: Employed in the discovery and development of new, high-performance crop protection agents with specific modes of action.
Material Science: Used in the research of advanced organic electronic materials and polymers where specific phosphorous-containing structures are required.
Process Chemistry: Utilized in route scouting and optimization for the scalable production of complex chiral molecules.
Academic Research: A valuable reagent for universities and research institutes studying novel organophosphorus chemistry and its applications.

Basic Information


Product Name	N-[(11bR)-2,6-Bis([1,1'-biphenyl]-4-yl)-8,9,10,11,12,13,14,15-octahydro-4-oxidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]-1,1,1-trifluoromethanesulfonamide
CAS No.	1261302-63-9
Molecular Formula	C47H35F3NO5PS
Molecular Weight	813.82 g/mol
Synonyms	(11bR)-4-[(Trifluoromethyl)sulfonamido]-2,6-bis(4-biphenylyl)-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-oxide; BINOL-derived chiral phosphoric acid triflimide derivative; Chiral BINOL phosphoramidate triflate; (R)-TRIP Triflimide Analog; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high chemical purity, which is essential for sensitive synthetic applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR (1H, 13C, 31P), and chiral analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, enantiomeric excess, and key physicochemical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines