Description

1,5-cyclooctadiene{(4S)-(+)-2-[(5S)-6-(diphenylphosphino)spiro[4.4]nona-1.6-dien-1-yl]-4,5-dihydro-4-(i-propyl)oxazole}iridiuM(I) tetrakis[3,5-bis(trifluoroMethyl)phenyl]borate is a highly specialized, chiral iridium(I) complex designed for advanced catalytic applications. This compound matters for its role as a precise and efficient catalyst in asymmetric synthesis, enabling the production of enantiomerically pure intermediates critical for high-value chemical manufacturing. It is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors where stereoselective transformations are paramount.

Application

• Asymmetric Hydrogenation: A key catalyst for the enantioselective reduction of prochiral olefins, imines, and ketones to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Enables the efficient and selective construction of complex, single-enantiomer molecular scaffolds for active pharmaceutical ingredients (APIs).
• Agrochemical Production: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators where biological activity is stereospecific.
• Fine Chemical and Fragrance Manufacturing: Facilitates the creation of enantiomerically pure flavor and fragrance compounds.
• Academic and Industrial R&D: Serves as a critical tool for methodological development in organic synthesis and catalysis research.
• Process Chemistry Optimization: Employed in scaling up and optimizing catalytic routes for more sustainable and cost-effective manufacturing processes.

Basic Information

Item	Details
Product Name	1,5-cyclooctadiene{(4S)-(+)-2-[(5S)-6-(diphenylphosphino)spiro[4.4]nona-1.6-dien-1-yl]-4,5-dihydro-4-(i-propyl)oxazole}iridiuM(I) tetrakis[3,5-bis(trifluoroMethyl)phenyl]borate
CAS No.	1194050-23-1
Molecular Formula	C71H58BF24IrNOP
Molecular Weight	~1620.9 g/mol
Synonyms	(S,S)-Ir-SpiroPAP; Iridium(I) (S,S)-spiroPAP complex; (S,S)-SpiroPAP Ir(I) BArF salt; Chiral iridium spiro phosphinooxazoline catalyst; Ir(S,S)-spiroPAP BArF; (S,S)-spiroPAP-Ir-COD BArF; Asymmetric hydrogenation catalyst Ir-spiroPAP; Iridium(I) complex with (4S,5S)-2-(6-(diphenylphosphanyl)spiro[4.4]nona-1,6-dien-1-yl)-4,5-dihydro-4-isopropyloxazole
EINECS	Contact for details

Quality Control

Every batch of our chiral iridium catalysts is produced and tested under strict quality control protocols to ensure exceptional purity and catalytic performance. Our rigorous analytical testing includes NMR, HPLC, and elemental analysis to verify identity, enantiomeric purity, and absence of critical metallic impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. This material is sensitive to oxygen and moisture; handle and store in a dry, controlled environment.

Specification

Item	Specification
Appearance	Orange to red crystalline or amorphous solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Enantiomeric Purity	≥ 99% ee
Iridium Content	Contact for details
Residual Solvents (GC)	Meets ICH guidelines
Elemental Analysis	Conforms to theoretical values

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.