Description

Methyl ((S)-1-((S)-2-(5-(4'-(2-((S)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-yl)-1H-imidazol-4-yl)-[1,1'-biphenyl]-4-yl)-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate is a sophisticated, high-purity chiral compound designed for advanced pharmaceutical research and development. This complex molecule serves as a critical intermediate or building block in the synthesis of novel therapeutic agents, particularly in targeted drug discovery programs. It is essential for medicinal chemists and process development scientists working in pharmaceutical, biotechnology, and fine chemical sectors who require precise, high-quality synthetic intermediates to accelerate their R&D pipelines.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential active pharmaceutical ingredients (APIs), particularly in oncology, antiviral, or metabolic disease research.
• Protease Inhibitor Research: Due to its structural motifs, it is utilized in the development of protease inhibitors, a major class of therapeutic agents.
• Peptidomimetic Drug Discovery: Serves as a core scaffold in the design and synthesis of peptidomimetics, which mimic peptides but with enhanced stability and bioavailability.
• Chemical Biology Probes: Used in the development of specialized molecular probes to study enzyme function and intracellular signaling pathways.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the commercial-scale manufacturing of complex drug candidates.
• Asymmetric Synthesis Catalyst/ Ligand Precursor: Potential use as a precursor for chiral ligands or organocatalysts used in stereoselective transformations.

Basic Information

Item	Details
Product Name	Methyl ((S)-1-((S)-2-(5-(4'-(2-((S)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-yl)-1H-imidazol-4-yl)-[1,1'-biphenyl]-4-yl)-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate
CAS No.	1007884-53-8
Molecular Formula	C41H51N7O5
Molecular Weight	721.89 g/mol
Synonyms	Carbamic acid, N-[(1S)-1-[[(2S)-2-[5-[4'-[2-[(2S)-1-[(2S)-2-amino-3-methyl-1-oxobutyl]-2-pyrrolidinyl]-1H-imidazol-4-yl][1,1'-biphenyl]-4-yl]-1H-imidazol-2-yl]-1-pyrrolidinyl]carbonyl]-2-methylpropyl]-, methyl ester; (S)-Methyl (1-((S)-2-(5-(4'-(2-((S)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-yl)-1H-imidazol-4-yl)-[1,1'-biphenyl]-4-yl)-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate; Biphenyl-imidazole-pyrrolidine carbamate derivative; CAS 1007884-53-8.
EINECS	Contact for details

Quality Control

Our methyl ((S)-1-((S)-2-(5-(4'-(2-((S)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-yl)-1H-imidazol-4-yl)-[1,1'-biphenyl]-4-yl)-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.