Description

Gadolinium, [10-[2-(hydroxy-kO)-3-hydroxy-1-(hydroxymethyl)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-kN1,kN4,kN7,kN10,kO1,kO4,kO7]-,monohydrate,[SA-8-1425362'5'-(R*,S*)]- (9CI) is a high-purity, complexed gadolinium compound designed for advanced research and development applications. This product is valued for its specific stereochemistry and chelated structure, which provides enhanced stability and targeted functionality. It is primarily utilized in the development of novel contrast agents for magnetic resonance imaging (MRI) and in specialized materials science research where precise metal coordination is critical.

Application

• Pharmaceutical Research & Development: A key intermediate or active component in the synthesis of next-generation gadolinium-based contrast agents (GBCAs) for diagnostic magnetic resonance imaging (MRI).
• Contrast Agent Precursor: Serves as a sophisticated building block for creating targeted MRI probes with potential applications in molecular imaging and disease-specific diagnostics.
• Coordination Chemistry Studies: Used as a model compound in academic and industrial research to study the properties of lanthanide complexes, ligand exchange kinetics, and thermodynamic stability.
• Materials Science: Investigated for use in the development of advanced materials, including luminescent probes, sensors, and catalysts that leverage the unique electronic properties of gadolinium.
• Radiopharmaceuticals: Potential use as a chelating scaffold for radiolabeling applications, though specific utility depends on the radiometal and intended diagnostic or therapeutic use.

Basic Information

Item	Details
Product Name	Gadolinium, [10-[2-(hydroxy-kO)-3-hydroxy-1-(hydroxymethyl)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-kN1,kN4,kN7,kN10,kO1,kO4,kO7]-,monohydrate,[SA-8-1425362'5'-(R*,S*)]- (9CI)
CAS No.	198637-52-4
Molecular Formula	C20H34GdN4O10 • H2O
Molecular Weight	Contact for details
Synonyms	Gadolinium DO3A-butrol monohydrate; Gadobutrol related compound; (R,S)-Gadolinium-10-[2,3-dihydroxy-1-(hydroxymethyl)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetate monohydrate; Gadolinium(III) DO3A-butrol complex; 1,4,7-Tris(carboxymethyl)-10-[1-(hydroxymethyl)-2,3-dihydroxypropyl]-1,4,7,10-tetraazacyclododecane gadolinium complex; Gadolinium chelate of butrol; A potential intermediate of Gadobutrol.
EINECS	Contact for details

Quality Control

Our Gadolinium, [10-[2-(hydroxy-kO)-3-hydroxy-1-(hydroxymethyl)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-kN1,kN4,kN7,kN10,kO1,kO4,kO7]-,monohydrate,[SA-8-1425362'5'-(R*,S*)]- (9CI) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Specifications are aligned with research-grade standards, and a comprehensive Certificate of Analysis (COA) detailing results for assay, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.